摘要
目的:探讨酮咯酸氨丁三醇复合小剂量舒芬太尼应用于肛肠手术术后镇痛中的临床安全性与可行性。方法:选取2021年1月-2022年3月泗洪县第一人民医院收治的60例肛肠手术患者为研究对象,随机分为舒芬太尼组(S组)和酮咯酸氨丁三醇复合舒芬太尼组(T组),各30例。观察并记录两组患者术后2 h、4 h、8 h、12 h、24 h、48 h静息与活动疼痛评分(VAS),术后48 h内自控次数及镇痛期间不良反应(恶心、呕吐、呼吸抑制及皮肤瘙痒)的发生率。结果:两组术后2 h、4 h、8 h、12 h、24 h、48 h静息与活动VAS评分比较,差异无统计学意义(P>0.05)。两组术后48 h内自控次数比较,差异无统计学意义(P>0.05)。两组呕吐、皮肤瘙痒发生率比较,差异无统计学意义(P>0.05);T组恶心的发生率明显低于S组,差异有统计学意义(P<0.05)。结论:酮咯酸氨丁三醇复合小剂量舒芬太尼在肛肠手术术后镇痛中的镇痛效果满意,不良反应小,值得应用并予以推广。
Objective:To explore the clinical safety and feasibility of ketorolac tromethamine combined with low-dose sufentanil in postoperative analgesia after anorectal surgery.Methods:Sixty patients undergoing anorectal surgery in First People's Hospital of Sihong County from January 2021 to March 2022 were selected as the study subjects and were randomly divided into S group(sufentanil group)and T group(ketorolac tromethamine combined with sufentanil group),with 30 patients in each group.The visual analogue scale(VAS)scores of resting and active pain at postoperative 2 h,4 h,8 h,12 h,24 h and 48 h,the number of selfcontrol within postoperative 48 h and the incidence of adverse reactions(nausea,vomiting,respiratory depression and skin itching)during analgesia periods were observed and recorded in two groups.Results:There was no significant difference in the resting and active VAS scores at postoperative 2 h,4 h,8 h,12 h,24 h and 48 h between the two groups(P>0.05).There was no significant difference in the number of self-control within postoperative 48 h between the two groups(P>0.05).There was no significant difference in the incidence of vomiting and skin itching between the two groups(P>0.05).The incidence of nausea in T group was significantly lower than in S group,and the difference was statistically significant(P<0.05).Conclusion:The clinical application of ketorolac tromethamine combined with low-dose sufentanil in postoperative analgesia after anorectal surgery has satisfactory analgesia effect and mild adverse reactions.It deserves the application and promotion.
作者
吴浩云
韩孟和
汤艳艳
赵素波
Wu Hao-yun;Han Meng-he;Tang Yan-yan;Zhao Su-bo(Department of Anesthesiology,First People's Hospital of Sihong County,Suqian 223900,Jiangsu Province,China)
出处
《中国社区医师》
2022年第31期56-58,共3页
Chinese Community Doctors
关键词
肛肠手术
酮咯酸氨丁三醇
小剂量舒芬太尼
术后镇痛
Anorectal surgery
Ketorolac tromethamine
Low dose
Sufentanil
Postoperative analgesia
