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生长抑素联合肠外营养支持在肠梗阻患者治疗中的应用效果研究 被引量:1

Study on the Application Effect of Somatostatin Combined with Parenteral Nutrition Support in the Treatment of Patients with Intestinal Obstruction
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摘要 目的探究肠梗阻患者接受生长抑素联合肠外营养支持治疗的应用效果。方法于2018年1月—2021年7月从宿迁市中医院收治的肠梗阻患者中抽选出65例患者为观察对象,均接受纠正水电解质平衡、胃肠减压等常规治疗。采取随机数表法将患者随机分成两组,32例接受生长抑素治疗患者入选对照组,33例接受生长抑素联合肠外营养支持治疗患者入选观察组。统计两组患者腹胀腹痛缓解率;观察两组患者临床指标改善情况,检测两组患者血液及炎症指标情况。结果治疗后,观察组患者腹痛腹胀缓解率为84.85%,明显高于对照组的62.50%,差异有统计学意义(χ^(2)=4.201,P<0.05);观察组患者胃肠减压量(259.43±68.24)mL、排气时间(3.92±1.18)d、住院时间(13.43±7.58)d均少于对照组,差异有统计学意义(P<0.05);观察组患者白蛋白(36.34±3.15)g/L、CRP(15.08±4.27)mg/L、血红蛋白(98.78±8.13)g/L和对照组相比,差异有统计学意义(P<0.05)。结论肠梗阻患者接受生长抑素联合肠外营养支持治疗,充分缓解了患者的临床症状,患者血液及炎性指标改善效果好,提升了患者的临床舒适度。 Objective To investigate the application effect of somatostatin combined with parenteral nutrition support therapy in patients with intestinal obstruction.Methods From January 2018 to July 2021,65 patients with intestinal obstruction admitted to Suqian Hospital of Traditional Chinese Medicine were selected as observation objects,and received routine treatment such as correction of water electrolyte balance and gastrointestinal decompression.The patients were randomly divided into two groups by random number table.32 patients receiving somatostatin therapy were selected as the control group,and 33 patients receiving somatostatin combined with parenteral nutritional support were selected as the observation group.The patients'abdominal distension and pain relief rates of the two groups were counted;the improvement of patients'clinical indexes of the two groups were observed;and the patients'blood and inflammation indexes of the two groups were detected.Results After treatment,the patients'abdominal pain and distension relief rate in the observation group was 84.85%,which was significantly higher than that of the control group 62.50%,and the difference was statistically significant(χ^(2)=4.201,P<0.05);the patients'gastrointestinal decompression volume(259.43±68.24)mL,exhaust time(3.92±1.18)d,and hospitalized time(13.43±7.58)d in the observation group were less than those in the control group,and the difference was statistically significant(P<0.05);the patients had albumin(36.34±3.15)g/L,CRP(15.08±4.27)mg/L,and hemoglobin(98.78±8.13)g/L in the observation group were statistically significant difference compared with the control group(P<0.05).Conclusion Patients with intestinal obstruction treated with somatostatin combined with parenteral nutrition support adequately relieved the clinical symptoms of the patients,and the patients'blood and inflammatory indexes improved well and enhanced their clinical comfort.
作者 王妞妞 WANG Niuniu(Department of Gastroenterology,Suqian Hospital of Traditional Chinese Medicine,Suqian,Jiangsu Province,223800 China)
出处 《世界复合医学》 2022年第10期143-146,共4页 World Journal of Complex Medicine
关键词 肠梗阻 生长抑素 肠外营养支持 机体代谢 免疫能力 Intestinal obstruction Somatostatin Parenteral nutrition support Body metabolism Immunity
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