摘要
目的探讨高压氧(HBO)治疗对老年患者脑梗死的疗效及超声血流动力学、血液流变学的影响。方法选取2020年1月至2021年6月海军军医大学第一附属医院收治的152例老年脑梗死患者作为研究对象,随机分为HBO治疗组和对照组,每组76例。比较2组患者治疗前后的神经功能评分、超声血液动力学和血液流变学变化情况。结果治疗后HBO治疗组患者美国国立卫生研究院卒中量表(NIHSS)评分低于对照组(P<0.05),中文版蒙特利尔认知评估量表(MoCA)评分和Barthel指数高于对照组(P<0.05);HBO治疗组患者的总有效率及血流动力学、血液流变学指标均优于对照组,差异有统计学意义(P<0.001)。结论与常规治疗相比,HBO治疗对老年脑梗死患者疗效更显著,具有促进患者认知功能和日常生活活动能力恢复、改善血液循环和血流动力学等积极意义。
Objective To investigate the effect of hyperbaric oxygen(HBO)therapy on cerebral infraction in elderly patients and its influence on hemodynamic and hemorheological parameters.Methods A total of 152 elderly patients with cerebral infarction admitted to the First Affiliated Hospital of Naval Medical University from January 2020 to June 2021 were selected as the research subjects and randomly divided into HBO group and control group,with 76 cases in each group.The changes of neurologic function scores and ultrasonic hemodynamic and hemorheological parameters before and after treatment were compared between the two groups.Results After treatment,the NIHSS scores of the patients in the HBO treatment group were lower than those of the control group(P<0.05),while the MoCA(Chinese version)score and Barthel Index in the HBO group were higher than those of the control group(P<0.05).The total effective rate,hemodynamic and hemorheological parameters of the patients in the HBO group were superior to those in the control group,with statistically significant differences(P<0.001).Conclusion Compared with conventional treatment,HBO treatment has a more significant effect on cerebral infarction in elderly patients.It can positively promote the recovery of elderly patients’cognitive function and activities of daily living,improve blood circulation and hemodynamic parameters.
作者
刘玲玉
王韦
曲艺
吴一娜
刘天佳
Liu Lingyu;Wang Wei;Qu Yi;Wu Yina;Liu Tianjia(Department of Ultrasound,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;Center for Cerebrovascular Diseases,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China)
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2022年第5期661-664,670,共5页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
脑梗死
高压氧
血流动力学
血液流变学
老年人
Cerebral infraction
Hyperbaric oxygen
Hemodynamics
Hemorheology
The elderly