摘要
目的探讨超声引导下微波消融治疗子宫肌瘤的有效性及安全性。方法选取2018年1月至2020年9月我院收治的120例子宫肌瘤患者作为研究对象,根据治疗方案不同将其分为对照组与观察组,各60例。对照组实施腹腔镜子宫肌瘤剔除术治疗,观察组实施超声引导下微波消融治疗。比较两组的临床疗效、手术相关指标、并发症发生情况、疼痛评分、炎症因子水平、子宫体积、肌瘤体积、生活质量。结果两组的治疗总有效率比较,差异无统计学意义(P>0.05)。观察组的手术时间、术后下床活动时间、住院时间均短于对照组,术中出血量少于对照组,差异具有统计学意义(P<0.05)。观察组的并发症总发生率为1.67%,低于对照组的11.67%,差异具有统计学意义(P<0.05)。术后第1、2、3天,观察组的视觉模拟评分法(VAS)评分均低于对照组,差异具有统计学意义(P<0.05)。术后第1、2、3天,观察组的C反应蛋白、白细胞介素-6水平均低于对照组,差异具有统计学意义(P<0.05)。术后,两组的子宫体积、肌瘤体积均小于术前,差异具有统计学意义(P<0.05);术后,两组的子宫体积、肌瘤体积比较,差异均无统计学意义(P>0.05)。术后,两组的生理、心理、环境及社会关系评分均升高,且观察组高于对照组,差异具有统计学意义(P<0.05)。结论超声引导下微波消融治疗子宫肌瘤的临床效果显著,可减少手术创伤,减轻术后疼痛感及炎症反应,减少术后并发症,提高患者术后生活质量,安全性良好,值得临床推广与应用。
Objective To investigate the efficacy and safety of ultrasound-guided microwave ablation in the treatment of uterine fibroids.Methods A total of 120 patients with uterine fibroids admitted in our hospital from January 2018 to September 2020 were selected as the study objects.According to different treatment regimens,the patients were divided into control group and observation group,with 60 cases in each group.The control group was treated with laparoscopic myomectomy,and the observation group was treated with ultrasound-guided microwave ablation.The clinical efficacy,operation related indexes,occurrence of complications,pain score,inflammatory factor levels,uterine volume,fibroid volume and quality of life were compared between the two groups.Results There was no significant difference in the total effective rate of treatment between the two groups(P>0.05).The operation time,postoperative ambulation time and hospitalization time of the observation group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,and the differences were statistically significant(P<0.05).The total incidence of complications in the observation group was 1.67%,which was lower than 11.67%in the control group,and the difference was statistically significant(P<0.05).On the 1st,2nd and 3rd after operation,the Visual Analogue Scale(VAS)score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).On the1st,2nd and 3rd after operation,the levels of C-reactive protein and interleukin-6 in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After operation,the uterine volume and fibroid volume of the two groups were smaller than those before operation,and the differences were statistically significant(P<0.05);after operation,there were no significant differences in uterine volume and fibroid volume between the two groups(P>0.05).After operation,the scores of physiology,psychology,environment and social relations increased in the two groups,those in the observation group were higher than the control group,and the differences were statistically significant(P<0.05).Conclusion Ultrasound-guided microwave ablation in the treatment of uterine fibroids has a significant clinical effect,it can decrease surgical trauma,alleviate postoperative pain and inflammatory response,reduce postoperative complications,improve postoperative quality of life of patients,and has good safety,which is worthy of clinical promotion and application.
作者
李冬梅
邹磊
周晓东
周兴伟
李武菊
邵越
LI Dongmei;ZOU Lei;ZHOU Xiaodong;ZHOU Xingwei;LI Wuju;SHAO Yue(Ankang Hospital of Traditional Chinese Medicine,Ankang 725000,China)
出处
《临床医学研究与实践》
2023年第1期62-65,共4页
Clinical Research and Practice
