摘要
目的 分析探讨二甲双胍分别联合达格列净、阿卡波糖在2型糖尿病中的治疗有效性及安全性。方法选取2018年1月—2020年12月福建省三明市清流县中医院收治的80例2型糖尿病患者为研究对象,随机分为两组,每组40例。对照组患者采用二甲双胍与阿卡波糖治疗,观察组患者采用二甲双胍与达格列净治疗。对两组患者治疗前后的血糖水平、血脂水平及不良反应发生情况与治疗效果进行比较。结果 治疗前,两组血糖水平、血脂水平对比,差异无统计学意义(P>0.05)。治疗后,观察组血糖水平、血脂水平优于对照组,差异有统计学意义(P<0.05)。观察组患者不良反应发生率低于对照组,治疗效果优于对照组,差异有统计学意义(P<0.05)。结论 二甲双胍分别联合达格列净、阿卡波糖在2型糖尿病中都具有一定的治疗效果,其中达格列净的效果很明显,有临床应用价值。
Objective To analyze the efficacy and safety of metformin combined with daggligin and acarbose in the treatment of type 2 diabetes.Methods 80 patients with type 2 diabetes who were admitted to Qingliu County Hospital of Traditional Chinese Medicine, Sanming City, Fujian Province from January 2018 to December 2020 were selected as the research objects, and they were randomly divided into two groups, with 40 patients in each group. The patients in the control group were treated with metformin and acarbose, while the patients in the observation group were treated with metformin and dagglinide. The blood glucose level, blood lipid level before and after treatment, adverse reactions and treatment effect of the two groups were compared.Results Before treatment, there was no statistically significant difference in blood glucose and blood lipid levels between the two groups(P>0.05). After treatment, the blood glucose level and blood lipid level in the observation group were better than those in the control group, and the difference was statistically significant(P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group, and the therapeutic effect was better than that in the control group, and the difference was statistically significant(P<0.05).Conclusion Dapagliflozin, metformin and acarbose all have certain therapeutic effects in type 2 diabetes. Among them, the effect of Dapagliflozin is obvious and has application value.
作者
谢远胜
XIE Yuansheng(Department of General Medicine,Qingliu County Hospital of Traditional Chinese Medicine,Sanming,Fujian Province,365300 China)
出处
《糖尿病新世界》
2022年第21期70-73,共4页
Diabetes New World Magazine
