摘要
目的探讨负压引流术对糖尿病足溃疡患者的治疗效果。方法选择2021年3月—2022年2月吉林市解放军第九六五医院治疗的糖尿病足溃疡患者78例为研究对象,根据患者接受治疗的顺序分组,将单号患者纳入对照组,将双号患者纳入观察组,各39例。对照组行常规治疗,观察组增加负压引流术的治疗环节。治疗后,比较两组患者的溃疡面愈合时间、抗生素使用时间、溃疡面肉芽组织血管内皮生长因子水平、白细胞介素-6和C反应蛋白水平。结果观察组患者溃疡面愈合时间和抗生素使用时间均短于对照组,溃疡面肉芽组织血管内皮生长因子水平高于对照组,白细胞介素-6和C反应蛋水平低于对照组,差异有统计学意义(P<0.05)。结论负压引流术可促进糖尿病足溃疡患者溃疡面的愈合,减少抗生素的使用时间,治疗效果较为理想。
Objective To investigate the effect of negative pressure drainage in the treatment of diabetic foot ulcer.Methods From March 2021 to February 2022,78 patients with diabetic foot ulcer treated in the 965th Hospital of the PLA were selected as the research objects.According to the order of treatment,patients with single number were included in the control group,and patients with double number were included in the observation group,39 cases in each group.The control group received routine treatment,while the observation group added negative pressure drainage.After treatment,the healing time of ulcer surface,antibiotic use time,vascular endothelial growth factor level in granulation tissue of ulcer surface,interleukin-6 and C-reactive protein level were compared between the two groups.Results The healing time of ulcer surface and antibiotic use time in observation group were shorter than those in control group,and the level of vascular endothelial growth factor in granulation tissue of ulcer surface was higher than that in control group,the levels of interleukin-6 and C-reactive protein were significantly lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion Negative pressure drainage can promote the healing of the ulcer surface of diabetic foot ulcer patients,reduce the use time of antibiotics,and the treatment effect is ideal.
作者
薛世军
XUE Shijun(Department of General Surgery,the 965 Hospital of the PLA,Jilin,Jilin Province,132000 China)
出处
《糖尿病新世界》
2022年第20期168-171,共4页
Diabetes New World Magazine
