摘要
孕产妇在妊娠期、分娩期和产褥期具有独特的解剖生理特点,容易发生生殖道细菌感染,病情进展可导致早产、流产、胎膜早破、羊膜腔感染、胎儿窘迫、死胎、产褥感染及脓毒血症等不良妊娠结局。目前,抗生素作为预防和治疗细菌感染最有效的药物,广泛应用于产科临床。值得注意的是,孕产妇的合理用药既要考虑到病情本身,同时也要兼顾到妊娠期、哺乳期的母婴双重安全,因此抗生素在产科的实际临床应用中仍存在许多问题,应得到更多的关注。就如何合理使用抗生素,结合不同时期、常见病种进行综述,有助于为妊娠期和哺乳期用药指导提供更多的理论依据。
Pregnant women have unique anatomical and physiological characteristics during pregnancy,delivery and puerperium,and are prone to genital tract bacterial infection.The progression of the disease can lead to adverse pregnancy outcomes such as premature birth,abortion,premature rupture of membranes,intra amniotic infection,fetal distress,stillbirth,puerperal infection,sepsis and so on.At present,antibiotics,as the most effective drugs to prevent and treat bacterial infections,are widely used in obstetric clinic.It is worth noting that rational use of drug for pregnant women should not only take into account the illness itself,but also take into account the safety of mother and child during pregnancy and lactation.Therefore,there are still many problems in the actual clinical application of antibiotics in obstetrics,which should be paid more attention to.This article reviews how to use antibiotics rationally,combined with different periods and common diseases,which is helpful to provide more theoretical basis for medication guidance during pregnancy and lactation.
作者
潘宇霞
项晴怡
白晓霞(审校)
PAN Yu-xia;XIANG Qing-yi;BAI Xiao-xia(Department of Obstetrics,Women′s Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China)
出处
《国际妇产科学杂志》
CAS
2022年第6期668-674,682,共8页
Journal of International Obstetrics and Gynecology
关键词
抗菌药
生殖道感染
细菌感染
产褥期感染
孕妇
Anti-bacterial agents
Reproductive tract infections
Bacterial infections
Puerperal infection
Pregnant women
