摘要
目的分析尿路感染诊断治疗中临床微生物检验的病原菌情况。方法选取2020年1月-2021年12月宜兴市中医医院收治的363例尿路感染患者,均行微生物检验,分析尿路感染致病菌的构成及分布情况以及不同性别、易感因素致病菌分布情况,并对尿路感染致病菌的耐药性进行分析。结果363例尿路感染患者的检验结果中革兰氏阴性菌301例,占比82.92%;革兰氏阳性菌58例,占比15.98%;真菌4例,占比1.10%。男性大肠埃希菌检出率低于女性,肺炎克雷伯菌、铜绿假单胞菌、金黄色葡萄球菌及粪肠球菌检出率高于女性(P<0.05)。部分致病菌在不同易感因素中检出率比较,差异有统计学意义(P<0.05)。药敏试验显示,革兰氏阴性菌与革兰氏阳性菌氨苄西林、红霉素、复方新诺明、左氧氟沙星、环丙杀星、青霉素、氯洁霉素耐药性比较,差异有统计学意义(P<0.05);二者庆大霉素耐药性比较,差异无统计学意义(P>0.05)。结论尿路感染的致病菌种类较多,其中以革兰氏阴性菌最为常见,各项病原菌在不同性别及易感因素病例中的检出情况不同,且耐药性各异。
Objective To analyze the pathogenic bacteria of clinical microbiological examination in the diagnosis and treatment of urinary tract infection.Methods A total of 363 patients with urinary tract infection admitted to Yixing Traditional Chinese Medicine Hospital from January 2020 to December 2021 were selected for microbiological examination.The composition and distribution of pathogenic bacteria in urinary tract infection and the distribution of pathogenic bacteria in different genders and susceptible factors were analyzed,and the drug resistance of pathogenic bacteria in urinary tract infection was analyzed.Results 363 cases of patients with urinary tract infection test results in 301 cases of gram-negative bacteria,accounting for 82.92%;gram-positive bacteria in 58 cases,accounting for 15.98%;fungi 4 cases,accounting for 1.10%.The detection rate of Escherichia coli in male was lower than that in female,and the detection rates of Klebsiella pneumoniae,Pseudomonas aeruginosa,Staphylococcus aureus and Enterococcus faecalis were higher than those in female(P<0.05).The detection rate of some pathogenic bacteria in different predisposing factors was statistically significant(P<0.05).Drug sensitivity test showed that there were significant differences in drug resistance between Gram-negative bacteria and Gram-positive bacteria ampicillin,erythromycin,cotrimoxazole,levofloxacin,ciprofloxacin,penicillin and chloramphenicol(P<0.05).There was no significant difference in gentamicin resistance between the two groups(P>0.05).Conclusion There are many types of pathogenic bacteria in urinary tract infections,among which gram-negative bacteria are the most common.The detection of various pathogens in cases of different genders and susceptibility factors is different,and the drug resistance is different.
作者
钱菲菲
周易
QIAN Fei-fei;ZHOU Yi(Department of Laboratory,Yixing Traditional Chinese Medicine Hospital,Yixing 214200,Jiangsu,China)
出处
《医学信息》
2022年第23期159-162,共4页
Journal of Medical Information
关键词
微生物检验
尿路感染
病原菌
革兰氏阴性菌
革兰氏阳性菌
大肠埃希菌
Microbiological test
Urinary tract infection
Pathogenic bacteria
Gram-negative bacteria
Gram-positive bacteria
Escherichia coli
