摘要
目的探讨社区人群围绝经期和绝经后妇女骨质疏松的发生情况及其影响因素。方法采用整群随机抽样抽取社区541例围绝经期和绝经后妇女为研究对象,行腰椎、髋关节骨密度检测并设为骨质诉疏松组(82例)和正常组(449例),建立数据库,logistic回归分析围绝经期和绝经后妇女骨质疏松影响因素。结果541例围绝经期及绝经后妇女检出骨质疏松82例,骨质疏松发生率15.16%,其中围绝经期267例,检出骨质疏松12例,骨质疏松发生率4.49%,绝经期274例,检出骨质疏松70例,骨质疏松发生率25.55%,围绝经期和绝经后骨质疏松发生率经χ2检验差异有统计学意义(χ2=48.171,P=0.000,P<0.05);经logistic多因素回归分析,年龄>60岁、BMI<24 kg/m^(2)、产次≥2(次)、绝经、糖尿病史、卧床跌倒史及素食均为发生骨质疏松的独立危险因素。初潮年龄<13岁、运动(每天>1 h)均为发生骨质疏松的保护性因素,差异均有统计学意义(均P<0.05)。结论骨质疏松为多重危险因素共同影响的综合性疾病,骨质疏松关键在于预防,了解各种危险因素对延缓骨质疏松的发生有重要的临床意义。
Objective To study the incidence and influencing factors of osteoporosis in perimenopausal and postmenopausal women in community.Methods 541 perimenopausal and postmenopausal women in the community were selected by cluster random sampling.The bone mineral density of lumbar spine and hip joints were measured.They were set up as osteoporosis group(82 cases)and normal group(449 cases).The database was established.The influencing factors of osteoporosis in perimenopausal and postmenopausal women were analyzed by logistic regression.Results 82 cases of osteoporosis were detected in 541 perimenopausal and postmenopausal women,and the incidence of osteoporosis was 15.16%.Among them,267 cases of perimenopausal women,12 cases of osteoporosis were detected,and the incidence of osteoporosis was 4.49%.274 cases of menopausal women,70 cases of osteoporosis were detected,and the incidence of osteoporosis was 25.55%.The incidence of perimenopausal and postmenopausal osteoporosis was statistically different by chi square test(χ2=48.171,P=0.000,P<0.05);logistic multivariate regression analysis showed that age>60,BMI<24 kg/m^(2),parity 2(times),menopause,diabetes,history of bed rest,and vegetarian diet were independent risk factors for osteoporosis.Age at menarche,age of<13 and exercise(>1 h per day)were all protective factors for osteoporosis,with statistical significance(P<0.05).Conclusion osteoporosis is a comprehensive disease affected by multiple risk factors.The key to osteoporosis is prevention.Understanding various risk factors is of great clinical significance to delay the occurrence of osteoporosis.
作者
李得利
吕珊珊
杜伟锋
LI De-Li;LV Shan-Shan;DU Wei-Feng(Department of Public Health,Yongkang Second People's Hospital,Jinhua,Zhejiang 321307,China)
出处
《中国妇幼保健》
CAS
2022年第24期4691-4694,共4页
Maternal and Child Health Care of China
基金
浙江省中医药现代化专项项目(2020ZX006)。
关键词
围绝经期
绝经期
骨质疏松
影响因素
Perimenopause
Menopause
Osteoporosis
Influencing factors
