摘要
目的探究稳定期精神分裂症患者在不同情绪启动下反应抑制的特点。方法纳入36例稳定期精神分裂症患者,以情绪视频作为情绪启动材料,采用经典Stroop范式(任务1)、Stroop范式变式(任务2)、经典Stroop范式与Go/Nogo范式相结合(任务3)3项任务对患者在正性、负性、中性情绪启动下的反应抑制进行测评,观察指标为反应时、正确率与Nogo错误率。结果患者在任务1中,反应时、正确率情绪主效应无统计学意义(P>0.05)。任务2中,正性情绪反应时高于中性情绪反应时[(1690.36±825.97)ms vs.(1429.76±657.93)ms,P=0.028]。任务3中负性情绪Nogo错误率高于正性情绪Nogo错误率[中位数12.50%(0,20.31%)vs.9.37%(6.25%,12.50%),P=0.019]。结论稳定期精神分裂症在不同情绪启动下、不同任务中反应抑制能力不同,相比Stroop范式任务,负性情绪在Go/Nogo范式任务中对反应抑制的影响更大。
Objective To explore the characteristics of reaction inhibition in stable schizophrenia under different emotional priming.Methods A total of 36 patients with stable schizophrenia were investigated for inhibition of response under positive,negative and neutral affective priming by using the classical Stroop paradigm(Task 1),its variant(Task 2),and the combination of classical Stroop paradigm and Go/Nogo paradigm(Task 3).The observation indexes were reaction time(RT),accruacy rate(ACC)and Nogo error rate.The emotional video was used as emotional priming material.Results In task 1,the emotional main effects of reaction and ACC were not significant(P>0.05).In task 2,the RT of positive emotion was higher than that of neutral emotion[(1690.36±825.97)ms vs.(1429.76±657.93)ms,P=0.028].The Nogo error rate of negative emotion in task 3 was higher than that of positive emotion[median:12.50%(0,20.31%)vs.9.37%(6.25%,12.50%),P=0.019].Conclusion In stable schizophrenia,the reaction inhibition abilities are different under different emotional priming and in different tasks.Compared with Stroop experimental task,negative emotions have a greater impact on reaction inhibition in Go/Nogo experimental task.
作者
徐若愚
李献云
XU Ruoyu;LI Xianyun(The Third Clinical Department,Beijing Huilongguan Hospital,Peking University Huilongguan Clinical Medical College,Beijing 100096,China)
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2022年第10期614-618,共5页
Chinese Journal of Nervous and Mental Diseases
基金
2022年河北省在读研究生创新能力培养资助项目(编号:CX ZZSS2022134)。
