摘要
前庭性偏头痛(VM)是以发作性前庭症状为主并伴有偏头痛特征的一类眩晕疾病。近年来,已有大量研究表明前庭性偏头痛与中医体质均存在先天遗传性特点,并证实了部分基因或位点的表达与前庭性偏头痛、中医体质分型存在一定关系。本文通过对VM与中医体质分型的遗传学机制进展进行论述,得出VM患者常见中医体质为气虚质、气郁质及痰湿质,推测其可能与VM部分突变位点存在关联,但因目前尚缺少相关证据,仍需大量研究验证。
Vestibular migraine(VM)is a type of vertigo disorder characterized by episodic vestibular symptoms paired with migraine headache,which belongs to the category of"vertigo"in TCM.In recent years,a large number of studies have shown that both vestibular migraine and TCM constitution have congenital genetic characteristics,and the expression of some genes or loci is related to vestibular migraine and TCM constitution typing.This paper discusses the research progress in genetic mechanisms of vestibular migraine and TCM constitution typing,coming to a conclusion that the common TCM constitutions in VM patients consist of the qi deficiency constitution,qi stagnation constitution and phlegm-dampness constitution,which is speculated to be associated with some mutation sites in vestibular migraine.However,due to the lack of relevant evidence at present,a large number of studies are still needed to verify it.
作者
滕鑫
荆涛
刘寅
孙莉
TENG Xin;JING Tao;LIU Yin;SUN Li(Graduate School,Changchun University of Chinese Medicine,Changchun 130117,China;Department of Geriatrics,Jilin Province Academy of Traditional Chinese Medicine,Changchun 130021,China)
出处
《长春中医药大学学报》
2023年第1期108-112,共5页
Journal of Changchun University of Chinese Medicine
基金
吉林省科技发展计划项目(20200201441JC)。
关键词
前庭性偏头痛
遗传学机制
基因
中医体质
研究进展
vestibular migraine
genetic mechanism
gene
TCM constitution
research progress
