摘要
目的观察慢性胃炎(Chronic gastritis,CG)患者中医证型分布,分析不同中医证型的CG患者幽门螺杆菌(Hp)感染情况。方法回顾分析2018年1月—2019年12月期间北京市广外医院收治的287例CG患者的病历资料。收集患者性别、年龄、病程、饮酒史、吸烟史等基线资料;统计分析患者中医证型分布情况,记录不同中医证型患者Hp感染情况。结果287例CG患者中,中医证型以脾胃湿热(29.97%)、脾胃虚寒证(25.78%)常见;共有230例患者Hp阳性,感染率为80.14%。不同中医证型CG患者中,Hp感染率位于前三的证型分别为脾胃虚寒(91.89%)、脾胃湿热(86.05%)、胃阴不足(77.55%)。Hp感染的230例CG患者中,男性患者以脾胃湿热证常见,女性以肝郁气滞证常见,性别间中医证型分布比较,差异有统计学意义(P<0.05);18~44岁、45~59岁患者均以脾胃湿热型常见,60~75岁患者以脾胃虚寒型常见;18~44岁与45~59岁年龄段中医证型分布比较,差异无统计学意义(P>0.05);18~44岁与60~75岁年龄段中医证型分布情况比较,差异有统计学意义(P<0.05);45~59岁与60~75岁年龄段中医证型分布比较,差异有统计学意义((P<0.05);病程<1年患者以肝郁气滞型最为常见,病程>10年患者以脾胃虚寒型最为常见;病程<1年与病程1~10年患者中医证型分布比较,差异有统计学意义(P<0.05);病程<1年与病程>10年患者中医证型分布比较,差异有统计学意义((P<0.05);病程1~10年与病程>10年患者中医证型分布比较,差异有统计学意义(P<0.05);饮酒、吸烟者均以脾胃湿热型常见,吸烟、饮酒者中医证型分布比较差异均有统计学意义(P<0.05)。结论Hp感染是CG的重要病因,Hp感染的CG患者中,中医证型以脾胃湿热型最为常见,且Hp感染的CG中医证型分布与性别、病程、饮酒、吸烟等均有一定联系,考虑可针对不同患者进行中医药辨证论治。
Objective To observe the distribution of traditional Chinese medicine(TCM)syndromes in patients with chronic gastritis(CG),and to analyze the Helicobacter pylori(Hp)infection of CG patients with different TCM syndromes.Methods The medical records of 287 CG patients admitted to Beijing Guangwai Hospital from January 2018 to December 2019 were reviewed and analyzed.The baseline data such as gender,age,course of disease,drinking history and smoking history were collected.The distribution of TCM syndromes was statistically analyzed,and the Hp infection of CG patients with different TCM syndromes was recorded.Results Among the 287 CG patients,the common TCM syndromes were dampness-heat in spleen and stomach(29.97%)and deficiency-cold in spleen and stomach(25.78%),and 230 patients were Hp positive,with the infection rate of 80.14%.Among CG patients with different TCM syndromes,the top three syndromes in terms of Hp infection rate were deficiency-cold in spleen and stomach(91.89%),dampness-heat in spleen and stomach(86.05%)and deficiency of stomach yin(77.55%).In the 230 CG patients with Hp infection,the syndrome of dampness-heat in spleen and stomach was common in male patients,while the syndrome of liver depression and qi stagnation was common in female patients.There was statistically significant difference in the distribution of TCM syndromes between genders(P<0.05).Among the patients aged 18~44 years old and 45~59 years old,dampness-heat in spleen and stomach was dominant,while in those aged 60~75 years old,deficiency-cold in spleen and stomach was dominant.There was no marked difference in the distribution of TCM syndromes between patients aged 18~44 years old and 45~59 years old(P>0.05),while distinct differences were found in the distribution of TCM syndromes between patients aged 18~44 years old and 60~75 years old(P<0.05)as well as between 45~59 years old and 60~75 years old(P<0.05).The syndrome of liver depression and qi stagnation was the most common in patients with a course of disease less than 1 year,while the syndrome of deficiency-coldin spleen and stomach dominated in patients with a course of disease more than 10 years.Obvious differences were observed in the distribution of TCM syndromes between patients with a course of less than 1 year and 1~10 years(P<0.05),a course of less than 1 year and more than 10 years(P<0.05),and a course of 1~10 years and more than 10 years(P<0.05).Dampness-heat in spleen and stomach was prevalent in patients with drinking and smoking history,and the distribution of TCM syndromes in them had statistically significant difference(P<0.05).Conclusion Hp infection was an important cause of CG.Among CG patients with Hp infection,dampness-heat in spleen and stomach was the most common syndrome,and the distribution of TCM syndromes of CG patients with Hp infection was related to gender,course of disease,drinking and smoking.Therefore,TCM syndrome differentiation and treatment can be carried out for different patients.
作者
马黎娟
孟祥
张娜娜
柏仙
宋莉红
MA Li-juan;MENG Xiang;ZHANG Na-na;BAI Xian;SONG Li-hong(Department of Emergency Medicine,Beijing Guangwai Hospital,Beijing 100055)
出处
《世界中西医结合杂志》
2022年第10期2062-2066,共5页
World Journal of Integrated Traditional and Western Medicine
基金
北京市西城区优秀人才培养资助项目(2019-XCRC-区卫计工委)。
关键词
慢性胃炎
中医证型
幽门螺杆菌感染
性别
病程
饮酒
吸烟
Chronic gastritis
TCM syndrome type
Helicobacter pylori infection
Gender
Course of disease
Drinking
Smoking
