摘要
目的分析卡前列素氨丁三醇联合缩宫素在剖宫产产后出血治疗中的临床效果。方法选取本院接受剖宫产手术并发生产后出血的76例患者为研究对象,分组方法为随机数字表法,将其分为对照组(38例)、研究组(38例)。对照组患者单用缩宫素治疗,研究组患者在对照组基础上联合卡前列素氨丁三醇治疗。比较两组患者产后2 h、12 h、24 h出血量,治疗前后凝血功能指标,以及治疗期间不良反应。结果与对照组比较,研究组产后2 h、12 h、24 h的出血量均更低;与治疗前比,治疗后两组凝血酶时间、活化部分凝血活酶时间均缩短,研究组相对对照组缩短;治疗后两组纤维蛋白原水平均升高,研究组相对对照组升高,差异均有统计学意义(P<0.05);两组治疗期间的不良反应总发生率经比较差异无统计学意义(P>0.05)。结论卡前列素氨丁三醇联合缩宫素治疗剖宫产产后出血能够有效降低患者产后出血量,改善凝血功能,应用效果显著。
Objective To analyze the clinical efficacy of carboprost tromethamine combined with oxytocin in the treatment of postpartum hemorrhage after cesarean section.Methods A total of 76 patients with postpartum hemorrhage who underwent cesarean section in our hospital were selected as the research objects.They were divided into the control group(38 cases)and the research group(38 cases)by random number table method.Patients in the control group were treated with oxytocin alone,while patients in the research group were treated with carboprost tromethamine on the basis of the control group.The blood loss at 2 h,12 h and 24 h after delivery,coagulation function before and after treatment,and adverse reactions during treatment were compared between the two groups.Results Compared with the control group,the blood loss at 2 h,12 h and 24 h after delivery in the research group was lower.Compared with before treatment,thrombin time and activated partial thromboplastin time shortened in the two groups after treatment,especially in the research group.Compared with before treatment,the levels of fibrinogen in the two groups increased after treatment,and the levels in the research group were higher,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion Carboprost tromethamine combined with oxytocin in the treatment of postpartum hemorrhage after cesarean section can effectively reduce the amount of postpartum bleeding and improve coagulation function,and the application effect is significant.
作者
杨颖超
Yang Yingchao(Department of Obstetrics and Gynecology,Changchun Maternity Hospital,Changchun,Jilin 130042,China)
出处
《实用妇科内分泌电子杂志》
2021年第34期41-43,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
剖宫产
产后出血
缩宫素
卡前列素氨丁三醇
凝血功能
Cesarean section
Postpartum hemorrhage
Oxytocin
Carboprost tromethamine
Blood coagulation function
