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糖尿病黄斑水肿患者抑郁与焦虑状态的临床分析

Clinical analysis of depression and anxiety in patients with diabetic macular edema
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摘要 目的:观察糖尿病黄斑水肿(Diabetic Macular Edema,DME)患者的焦虑、抑郁情况,为进一步预防、干预相关心理负面情绪提供理论依据。方法:选取深圳市宝安区福永人民医院2020年10月至2021年12月接诊的100例DME患者作为观察组,并依据疾病程度分为轻中重度三组;同时以100例2型糖尿病(Type 2 Diabetes Mellitus,T2DM)患者作为对照组,通过抑郁自评量表(Self-rating Depression Scale,SDS)和焦虑自评量表(Self-rating Anxiety Scale,SAS)比较两组及不同程度DME组别的焦虑、抑郁情况。结果:轻度、中度、重度DME患者的SAS评分分别为(56.179±7.126)分、(62.265±10.344)分、(76.815±7.806)分,均显著高于对照组的(47.362±7.542)分,差异有统计学意义(P<0.01)。轻度、中度、重度DME患者的SDS评分分别为(56.744±8.522)分、(66.971±7.990)分、(76.185±6.152)分,均显著高于对照组的(48.317±7.849)分,差异有统计学意义(P<0.01)。此外,DME严重程度与SAS评分、SDS评分均呈显著正相关(rs=0.633,P<0.05;rs=0.740,P<0.05)。结论:DME患者具有更严重的抑郁、焦虑情绪,且随着病情加重,焦虑及抑郁情绪逐渐加重,临床医师需及时采取心理干预措施,以提高其原发病的疗效及生活质量。 Objective:To observe the anxiety and depression of patients with Diabetic Macular Edema(DME),and to provide theoretical basis for further prevention and intervention of related negative psychological emotions.Methods:100 cases of DME patients admitted to Fuyong People’s Hospital of Bao‘an District,Shenzhen from October 2020 to December 2021 were selected as the observation group,and divided into three groups according to the severity of disease:mild,moderate and severe.At the same time,100 patients with Type 2 Diabetes Mellitus(T2DM)were selected as the control group.Self-rating Depression Scale,SDS and Self-rating Anxiety Scale(SAS)were used to compare the anxiety and depression of the two groups and the DME groups with different degrees.Results:The SAS scores of mild,moderate and severe DME patients were(56.179±7.126)points,(62.265±10.344)points and(76.815±7.806)points,respectively,which were significantly higher than that of the control group(47.362±7.542)points,and the difference was statistically significant(P<0.01).The SDS scores of mild,moderate and severe DME patients were(56.744±8.522)points,(66.971±7.990)points and(76.185±6.152)points,respectively,which were significantly higher than those of the control group(48.317±7.849)points,and the difference was statistically significant(P<0.01).In addition,DME severity was positively correlated with SAS score and SDS score(rs=0.633,P<0.05;rs=0.740,P<0.05).Conclusion:DME patients have more serious depression and anxiety,and with the aggravation of the disease,anxiety and depression gradually aggravated,clinicians need to take timely psychological intervention measures,in order to improve the ef ficacy of the primary disease and quality of life.
作者 黎国敏 LI Guomin(Department of Endocrinology,Fuyong People’s Hospital of Bao‘an District,Shenzhen Guangdong 518103)
出处 《当代医药论丛》 2023年第1期83-86,共4页
基金 深圳市宝安区科创委基础研究项目(20210430160631001)。
关键词 糖尿病黄斑水肿 焦虑 抑郁 diabetic macular edema Anxiety depression
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