摘要
目的探究女性不孕症患者接受性激素六项指标测定辅助检查的临床诊断价值。方法选取吴川市妇幼保健计划生育服务中心在2018年7月—2020年10月期间收治的女性不孕症患者与妇科门诊女性共87例展开临床对照研究,其中44例不孕症患者为研究组、43名生殖健康者为对照组,并将研究组44例患者按照有无月经紊乱分为研究组A(n=23,月经紊乱)、研究组B(n=21,月经正常),比较患者促卵泡生成素(FSH)、泌乳素(PROL)、黄体生成素(LH)、雌二醇(E_(2))、孕酮(P)、睾酮(T)指标水平。结果研究组患者FSH(11.52±2.75)mIU/L、LH(12.86±3.25)IU/L、PROL(24.98±10.16)ng/mK指标水平均高于对照组,差异有统计学意义(t=6.514、6.636、4.511,P<0.05),两组E_(2)、P、T指标水平比较,差异无统计学意义(P>0.05);研究组A患者FSH、LH、PROL指标水平均高于研究组B,差异有统计学意义(P<0.05),两组E_(2)、P、T指标水平比较,差异无统计学意义(P>0.05)。结论与生殖健康女性相比,女性不孕症患者FSH、LH、PROL指标水平异常偏高,且女性不孕症伴月经紊乱患者FSH、LH、PROL指标水平高于月经正常患者,检测可精准测定以上指标具体值,为临床诊断不孕症提供可靠依据。
Objective To investigate the clinical diagnostic value of female infertility patients receiving the auxiliary examination of sex hormone six indexes determination.Methods A total of 87 female infertility patients admitted to Wuchuan Maternal and Child Health and Family Planning Service Center from July 2018 to October 2020 and women in gynecological outpatient clinics were included in the clinical control study.Among them,44 infertility patients were the study group and 43 reproductive health patients were the control group.The 44 patients in the study group were divided into study group A(n=23,menstrual disorders)and study group B(n=21,normal menstruation)according to the presence or absence of menstrual disorders.The six sex hormone indices were measured in patiemts,and the differences between the levels of follicle stimulating hormone(FSH),prolactin(PROL),luteinizing hormone(LH),estradiol(E_(2)),progesterone(P),and testosterone(T)indices of the patients were compared.Results The levels of FSH(11.52±2.75)mIU/L,LH(12.86±3.25)IU/L and PROL(24.98±10.16)ng/mK indexes were higher in the study group than in the control group,and the differences were statistically significant(t=6.514,6.636,4.511,P<0.05).The difference of levels of E_(2),P and T indexes between the two groups were not statistically significant(P>0.05).The levels of FSH,LH and PROL were higher in study group A than in study group B,the difference was statistically significant(P<0.05),and there was no statistically significant difference between the levels of E_(2),P and T between the two groups(P>0.05).Conclusion Compared with reproductively healthy women,the levels of FSH,LH,and PROL indexes were abnormally high in female infertility patients,and the levels of FSH,LH,and PROL indexes in female infertility patients with menstrual disorders were higher than in female with normal menstruation,and the test can accurately determine the specific values of the above indexes and provide a reliable basis for clinical diagnosis of infertility.
作者
郑远华
ZHENG Yuanhua(Department of Laboratory,Wuchuan Maternal and Child Health and Family Planning Service Center,Zhanjiang,Guangdong Province,524500 China)
出处
《系统医学》
2022年第20期66-68,73,共4页
Systems Medicine
关键词
女性
不孕症
性激素六项指标测定
临床诊断
Female
Infertility
Sex hormone six indexes determination
Clinical diagnosis
