摘要
研究乳化剂及增稠剂对低黏度乳液及其液晶情况和喷雾效果的影响,从而筛选出适合二元气雾包装的低黏度可喷雾乳液的乳化剂及增稠剂,并通过稳定性、液晶分布、喷雾状况、功效测试对其进行初步考察。乳化剂采用糖苷类乳化剂、醇酯类乳化剂和聚甘油类乳化剂(单一使用和复配使用),研究其对乳液黏度及液晶的影响;增稠剂采用黄原胶、卡波姆、丙烯酸(酯)类/山嵛醇聚醚-25甲基丙烯酸酯共聚物、丙烯酰二甲基牛磺酸铵/VP共聚物、丙烯酸(酯)类/C10-30烷醇丙烯酸酯交联聚合物及其组合,研究其对乳液黏度、稳定性及喷出状态的影响。实验结果表明:聚甘油类乳化剂适合制备出低黏度液晶乳液,并在气雾瓶中容易泵出且张角较大;将得到的低黏度乳液置于二元气雾包装中,乳液黏度越低,其喷雾张角越大,但黏度越低对高温稳定性及离心稳定性的挑战越大;乳化剂复配可使液晶乳化粒径更小,颗粒更均一。其所得低黏度液晶乳液涂抹于身体后,水分含量显著提高,经皮失水量(TEWL)显著降低,证明该乳液具有很好的保湿和修护效果。
The effects of emulsifiers and thickeners on low-viscosity liquid crystal emulsions and their liquid crystal and ejection in binary aerosol propellants were studied,then the stability and ejection and liquid crystal of the low-viscosity emulsions were monitored by investigating their emulsifiers and thickener.Glycoside emulsifiers,alcohol ester emulsifiers and polyglycerol emulsifiers(single use and mixed use)were used to study their effects on emulsion viscosity and liquid crystal.Xanthan gum,Carbomer,Acrylates/Beheneth-25 Methacrylate Copolymer,Ammonium Acryloyldimethyltaurate/Vp Copolymer,Acrylates/C10-30 Alkyl Acrylate Crosspolymer,and their combinations were used to study the effects on viscosity,the stability and ejection state of the emulsions.The results show that polyglycerol emulsifier is suitable for low-viscosity liquid crystal emulsions,in addition,it is more easily to pump out in binary aerosol propellants with large opening angle.The open angle of low-viscosity emulsions in binary aerosol propellants is wider when the viscosity is lower,however,it is very difficult to prepare low viscosity emulsions with good high temperature stability as well as excellent centrifugal stability.Thickeners play a very important role in stability.Low-viscosity and stable emulsions can be prepared by Acrylates/C10-30 Alkyl Acrylate Crosspolymer combined with Xanthan gum.The liquid crystal emulsions have smaller particle size with compounding emulsifier and the formation of liquid crystals is beneficial to the stability of emulsions.When the low viscosity liquid crystal emulsion is applied to the body,the moisture content increases significantly,and the transepidermis water loss(TEWL)decreases significantly,which proves that the emulsion has good moisturizing and repairing effects.
作者
郭芳
Fang Guo(Xingzhi Yumei(Shanghai)Biotechnology Co.,Ltd,Shanghai 200233,China)
出处
《日用化学工业（中英文）》
CAS
北大核心
2023年第1期16-23,共8页
China Surfactant Detergent & Cosmetics
基金
星智豫美(上海)生物科技有限公司内部项目(XZYM2021-001)。
关键词
液晶乳液
低黏度乳液
稳定性
喷出测试
liquid crystal emulsion
low-viscosity emulsions
stability
Ejection test
