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39例慢型克山病死亡病例的临床特征和死亡原因分析

Clinical characteristics and causes of death in 39 cases of chronic Keshan disease
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摘要 目的探讨慢型克山病死亡病例的临床特征和死亡原因。方法回顾性分析2016年3月至2020年8月在泾川县人民医院反复住院的39例慢型克山病病例死亡前最后1次临床资料,包括性别、年龄、病程、临床症状和体征、胸部X线片、心电图、心脏超声心动图、死亡原因等,分析慢型克山病病例死亡相关的临床特征。结果共纳入39例慢型克山病死亡病例,其中,男性27例(69.2%),女性12例(30.8%);年龄为(62.64±8.63)岁;病程中位数为5年。呼吸困难[37例(94.9%)]和水肿[33例(84.6%)]为主要临床症状。全部病例均有不同程度的心脏扩大、肺淤血征象,以及心电图异常改变。死亡原因中,心脏性猝死18例(46.2%),心力衰竭11例(28.2%),心源性休克5例(12.8%),心力衰竭合并心源性休克3例(7.7%),其他原因2例(5.1%)。结论呼吸困难和水肿为慢型克山病死亡病例的主要临床特征,心脏性猝死、心力衰竭、心源性休克是其死亡的三大常见原因。 Objective To investigate the clinical characteristics and causes of death of chronic Keshan disease cases.Methods A retrospective analysis was conducted on the last clinical data of 39 death cases of chronic Keshan disease who were repeatedly hospitalized in Jingchuan County People's Hospital from March 2016 to August 2020 before their death,including gender,age,course of disease,clinical symptoms and signs,chest X-ray,electrocardiogram,cardiac echocardiography,causes of death,etc.,and analysis was made on the clinical characteristics related to the death of chronic Keshan disease cases.Results Among the 39 death cases of chronic Keshan disease,27 cases(69.2%)were male and 12 cases(30.8%)were female.The age was(62.64±8.63)years old,and the median course of disease was 5 years.Dyspnea[37 cases(94.9%)]and edema[33 cases(84.6%)]were the main clinical symptoms.All cases had varying degrees of cardiac enlargement,pulmonary congestion signs,and abnormal changes in electrocardiogram.Among the causes of death,18 cases(46.2%)were sudden cardiac death,11 cases(28.2%)were heart failure,5 cases(12.8%)were cardiogenic shock,and 3 cases(7.7%)were heart failure combined with cardiogenic shock,and 2 cases(5.1%)had other causes.Conclusion Dyspnea and edema are the main clinical characteristics of death cases of chronic Keshan disease,sudden cardiac death,heart failure and cardiogenic shock are the three common causes of death.
作者 王平 李萍 邵建赟 康建业 Wang Ping;Li Ping;Shao Jianyun;Kang Jianye(Department of Cardiology,Jingchuan County People's Hospital,Pingliang 744300,China;Department for Endemic Disease Prevention and Control,Gansu Center for Disease Prevention and Control,Lanzhou 730000,China;Jingchuan County Center for Disease Prevention and Control,Pingliang 744300,China)
出处 《中华地方病学杂志》 CAS 北大核心 2022年第12期1004-1007,共4页 Chinese Journal of Endemiology
基金 甘肃省科技厅自然科学基金(18JR3RA042) 2021年卫生健康标准评估项目 平凉市科技局科研项目(平科任自[2021]8号)。
关键词 克山病 临床特征 心脏性猝死 心力衰竭 心源性休克 Keshan disease Clinical characteristics Sudden cardiac death Heart failure Cardiogenic shock
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