摘要
目的:探讨新生化颗粒联合去氧孕烯炔雌醇片对宫内节育器(IUD)所致异常子宫出血(AUB)的治疗价值。方法:纳入2019年10月—2020年10月我院诊治的102例IUD所致AUB患者作为研究对象,按随机抽签法分为对照组(n=51)和实验组(n=51)。对照组采用去氧孕烯炔雌醇片治疗,实验组在对照组基础上加用新生化颗粒进行治疗,比较两组总体疗效,月经状况(月经周期、月经量、经期),贫血相关指标[红细胞计数(RBC)、血红蛋白(HGB)、红细胞压积(HCT)]及不良反应。结果:治疗后,实验组(总有效率为96.08%,高于对照组的84.31%(P<0.05));实验组月经周期、月经量、经期、RBC、HGB、HCT水平优于对照组(P<0.05);实验组不良反应发生率与对照组比较,差异无统计学意义(P>0.05)。结论:新生化颗粒联合去氧孕烯炔雌醇片治疗IUD所致AUB的疗效确切,可改善患者月经状况及贫血相关指标,且安全性良好。
Objective: To investigate the therapeutic value of Xinshenghua granules combined with deoxygestrel ethinylestradiol tablets in the treatment of abnormal uterine bleeding(AUB) caused by intrauterine device(IUD). Methods:A total of 102 patients with AUB caused by IUD who were treated in our hospital from October 2019 to October 2020 were included in the study. They were divided into control group(51 cases) and experimental group(51 cases) according to the random lottery method. The control group was treated with deoxygestrel ethinylestradiol tablets, and the experimental group was treated with Xinshenghua granules+desogestrel ethinylestradiol tablets. The overall efficacy, menstrual status(menstrual cycle, menstrual volume, menstrual period), anemia-related indicators [red blood cell count(RBC), hemoglobin(HGB),hematocrit(HCT)] and adverse reactions were compared between the two groups. Results: After treatment, the total effective rate of the experimental group was 96.08%, which was higher than 84.31% of the control group(P<0.05). The levels of menstrual cycle, menstrual volume, menstrual cycle, RBC, HGB and HCT in the experimental group were better than those in the control group(P<0.05). There was no significant difference in the incidence of adverse reactions between the experimental group and the control group(P>0.05). Conclusion: Xinshenghua granule combined with deoxypregnenethinylestradiol tablets is effective in the treatment of AUB induced by IUD, and can improve the menstrual status and anemia related indexes of patients, with good safety.
作者
黄巧美
郭小莺
HUANG Qiaomei;GUO Xiaoying(Department of Family Planning,the Maternal and Child Health Hospital of Minhou County,Minhou 350100,Fujian,China)
出处
《中国药物滥用防治杂志》
CAS
2022年第12期1862-1865,共4页
Chinese Journal of Drug Abuse Prevention and Treatment
关键词
宫内节育器
异常子宫出血
新生化颗粒
去氧孕烯炔雌醇片
Intrauterine device
Abnormal uterine bleeding
Xinshenghua granules
Deoxygestrel ethinylestradiol tablets
