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新生儿在输血过程中禁食或喂养对肠氧合变化的影响

Studies on the Effect of Fasting or Feeding on Intestinal Oxygenation in Neonates during Blood Transfusion
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摘要 目的 探讨新生儿在输血过程中给予禁食或喂养对肠氧合变化的影响。方法 选取2021年6月至2022年7月以来云南省某三级甲等儿童专科医院新生儿科接受红细胞输注治疗的新生儿,根据输血过程中是否继续喂养,随机数字表法随机分组,分为禁食组及喂养组。使用近红外组织血氧参数无损监测仪对其指标进行检测,新生儿在输注红细胞过程中给予禁食或喂养时的肠道组织氧饱和度(rSO_(2))变化。共纳入符合条件的新生儿59例,禁食组21例,喂养组38例。2组患儿在性别、胎龄(早产儿纠正胎龄)、日龄上差异均无统计学意义(P> 0.05)。结果 在红细胞输注过程中禁食组禁食前、禁食段、禁食后肠道rSO_(2) (%)平均值分别是[(54.77±6.49)、(55.18±7.64)、(55.94±6.46)];喂养组喂养前、喂养段、喂养后肠道rSO_(2) (%)平均值分别是[(55.35±6.11)、(57.79±6.37)、(58.89±5.55)]。2组禁食/喂养前、禁食/喂养段、禁食/喂养后的分组间比较,差异均无统计学意义(P> 0.05)。结论 新生儿输注红细胞过程中给予禁食或喂养对比禁食或喂养前后的肠道rSO_(2)变化范围不大,在原喂养基础上可以考虑在输血过程中继续喂养。 Objective To investigate the effect of fasting or feeding on intestinal oxygenation in neonates during the blood transfusion.Methods From June 2021 to July 2022,a total of 59 eligible neonates who received the red blood cell infusion treatment in the newborn department of a third class A children’s special hospital in Yunnan Province were randomly divided into the fasting group and the feeding group,with 21 in the fasting group and 38 in the feeding group according to whether they continued to be fed during the blood transfusion.The nearinfrared tissue blood oxygen parameter nondestructive monitor was used to detect its indicators and observe the changes of intestinal tissue oxygen saturation(r SO_(2)) in neonates during the fasting or feeding in the caurse of red blood cell infusion.Results There was no significant difference between the two groups in gender,gestational age(corrected gestational age of premature infants) and age of days(P > 0.05).The average values of RSO_(2) in intestinal tract before,during and after the fasting in the fasting group in the caurse of red blood cell infusion(%) were(54.77±6.49),(55.18±7.64) and(55.94±6.46) respectively;The average values of RSO_(2) in intestinal tract before,during and after the feeding in the feeding group( %) were( 55.35±6.11),( 57.79±6.37) and (58.89±5.55) respectively.There was no significant difference between the two groups before fasting/feeding,during fasting/feeding and after fasting/feeding(P > 0.05).Conclusion The change range of rSO_(2) in the intestine of neonates before and after fasting or feeding compared with fasting or feeding in the process of red blood cell transfusion is small,and continuous feeding can be considered in the process of blood transfusion on the basis of the original feeding.
作者 袁媛 尹丽娟 漆永林 YUAN Yuan;YIN Lijuan;QI Yonglin(Dept.of Neonatology,Kunming Children’s Hospital,Kunming Yunnan 650034;School of Nursing,Dali University,Dali Yunnan 671003,China)
出处 《昆明医科大学学报》 CAS 2023年第1期168-172,共5页 Journal of Kunming Medical University
基金 云南省教育厅科学研究基金资助项目(2020J0225) 昆明市卫生健康委员会卫生科研基金资助项目(2021-14-04-008)。
关键词 输血 禁食或喂养 谱学 近红外线 肠组织氧饱和度 Blood transfusion Fasting or feeding Spectroscopy Near infrared ray Intestinal tissue oxygen saturation
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