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椎管内麻醉与全身麻醉对膝关节或髋关节置换术后手术部位感染发生率影响的meta分析 被引量:4

Meta-Analysis of the Impact of Neuraxial Anesthesia and General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty
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摘要 目的系统评价椎管内麻醉与全身麻醉对膝关节或髋关节置换术后手术部位感染(SSI)发生率的影响。方法计算机检索PubMed、Web of Science和MEDLINE数据库中有关椎管内麻醉与全身麻醉对膝关节或髋关节置换术后SSI发生率影响的随机对照试验,检索时限为建库至2022年9月。使用Rev Man 5.4软件进行meta分析,比较两组术后SSI发生率。结果共纳入15篇文献,涉及患者353169例。meta分析结果显示,椎管内麻醉组置换术后SSI发生率低于全身麻醉组,差异有统计学意义(P<0.05)。亚组分析结果表明椎管内麻醉可降低膝关节或髋关节置换术后SSI发生率(P<0.05)。漏斗图显示研究无发表偏倚。结论椎管内麻醉有助于降低膝关节或髋关节术后SSI发生率,值得临床进一步推广。 Objective To systemically evaluate the impact of neuraxial anesthesia and general anesthesia on the incidence of surgical site infection(SSI)after knee or hip arthroplasty.Methods Randomized controlled trials of the effect of neuraxial anesthesia and general anesthesia on the incidence of SSI after knee or hip arthroplasty were searched by computer in PubMed,Web of Science and MEDLINE databases.The retrieval time limit was from the inception to September 2022.Meta-analysis of SSI after knee or hip arthroplasty between neuraxial anesthesia and general anesthesia groups was performed by Rev Man 5.4 software.Results A total of 15 articles were included with 353169 cases.The meta-analysis result showed that the incidence of SSI in the neuraxial anesthesia group was lower than that in the general anesthesia group with statistical significance(P<0.05).Subgroup analysis results exhibited that neuraxial anesthesia could reduce the incidence of SSI following knee or hip arthroplasty(P<0.05).The funnel plot showed no publication bias.Conclusion Neuraxial anesthesia had beneficial effects in decreasing the development of SSI after knee and hip arthroplasty,which is worthy of further promotion in the clinical field.
作者 叶杏子 YE Xingzi(Anesthesiology Department,Zhejiang Greentown Cardiovascular Hospital,Hangzhou 310050,China)
出处 《河南医学研究》 CAS 2023年第2期240-244,共5页 Henan Medical Research
关键词 椎管内麻醉 全身麻醉 膝关节置换术 髋关节置换术 手术部位感染 META分析 neuraxial anesthesia general anesthesia knee arthroplasty hip arthroplasty postoperative surgical site infection meta analysis
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