摘要
目的探讨应用射频消融治疗原发性甲状腺功能亢进症的可行性及安全性。资料与方法回顾性分析2019年10月—2021年3月桂林医学院第二附属医院原发性甲状腺功能亢进症11例,根据患者自身情况行超声引导下射频消融术(射频消融组),同期17例开放手术患者作为对照组,比较两组手术操作时间、平均住院时间、术后并发症、颈部疼痛程度、美容满意度、术前及术后不同时间点甲状腺功能和甲状旁腺激素水平。结果射频消融组平均手术时间[(40.4±7.4)min]较对照组[(90.8±13.4)min]更短(P=0.024),住院时间[(6.5±2.3)d]较对照组[(16.0±3.8)d]更短(P=0.043),术后低钙血症发生率[(0/11)例]较照组[(6/17)例]更低(P=0.033);两组术后6个月促甲状腺激素、三碘甲腺原氨酸、甲状腺素水平等差异无统计学意义(P>0.05)。与对照组相比,射频消融组术后颈部疼痛和吞咽不适少,美容满意程度高(P<0.05)。结论超声引导下射频消融术治疗原发性甲状腺功能亢进症安全、有效、可行,对美容形象影响少,值得推广。
Purpose To investigate the feasibility and safety of radiofrequency ablation in the treatment of primary hyperthyroidism.Materials and Methods Retrospective analysis was performed on 11 patients with primary hyperthyroidism in the Second Affiliated Hospital of Guilin Medical University from October 2019 to March 2021,who received ultrasound-guided radiofrequency ablation(radiofrequency ablation group)according to their own conditions,and 17 patients with open surgery(control group)during the same period.The operation time,mean length of hospital stay,postoperative complications,degree of neck pain,aesthetic satisfaction,and thyroid function and parathyroid hormone levels at different time points before and after surgery were compared between the two groups.Results In the radiofrequency ablation group,the mean operation time[(40.4±7.4)min]was significantly shorter than that in the control group[(90.8±13.4)min](P=0.024),the length of hospital stay[(6.5±2.3)days]was significantly less than that in the control group[(16.0±3.8)days](P=0.043),and the incidence of postoperative hypocalcemia[(0/11)cases]was significantly lower than that in the control group[(6/17)cases](P=0.033).There was no significant difference in thyroid stimulating hormone,triiodothyronine,tyroxine and other thyroid function indexes between the two groups 6 months after surgery(P>0.05).Compared with the control group,the postoperative neck pain and swallowing discomfort were significantly less in the radiofrequency ablation group,and the aesthetic satisfaction in the radiofrequency ablation group was significantly higher than that in control group(P<0.05).Conclusion Ultrasound-guided radiofrequency ablation in the treatment of primary hyperthyroidism is safe,effective,feasible,and has little effect on cosmetic image,so it is worth promoting.
作者
王桂林
黄仁相
洪运虎
俸瑞发
WANG Guilin;HUANG Renxiang;HONG Yunhu;FENG Ruifa(Department of Breast and Thyroid Surgery,the Second Affiliated Hospital of Guilin Medical University,Guilin 541199,China)
出处
《中国医学影像学杂志》
CSCD
北大核心
2023年第1期20-24,共5页
Chinese Journal of Medical Imaging
基金
广西医疗卫生重点培育学科建设项目
广西壮族自治区卫生健康委员会计划项目(Z20200455)。
