摘要
苦豆子为豆科槐属植物,其全草、根及种子皆可入药,具有清热润燥、止痛和杀虫的功效。苦豆子中含有生物碱、黄酮、挥发油、多糖、有机酸、香豆素及微量元素等化学成分。现代药理学研究发现,苦豆子具有抗肿瘤、抗炎、镇痛、抗菌、免疫调节、保护中枢神经系统、保护心血管系统和保护肝脏等药理作用。苦豆子还具有一定的毒性,主要表现在对中枢神经系统、心血管系统与肝毒性。本文综述了近30年来苦豆子不同药用部位的化学成分、药理作用及毒性等研究进展,可为其后续研究提供理论依据。
Sophora alopecuroides is a plant of the genus Sophora, and its whole grass, roots and seeds can be used as medicine, which has the effects of clearing away heat and moisturizing dryness, relieving pain and killing insects. S. alopecuroides contains alkaloids, flavonoids,volatile oil, polysaccharides, organic acids, coumarins, trace elements and other chemical components. Modern pharmacological studies have found that S. alopecuroides has pharmacological effects such as anti-tumor, anti-inflammation, analgesia, antibacterial, immune regulation, protection of central nervous system, cardiovascular system, liver and so on. In addition, S. alopecuroides also has certain toxicity,mainly on the central nervous system, cardiovascular system and hepatotoxicity. This paper systematically summarizes the studies on the chemical constituents of different parts, pharmacological effects, toxicity of S. alopecuroides in the past 30 years, which would provide a theoretical basis for the follow-up research of S. alopecuroides.
作者
陈静
刘洋
支文冰
安玉叶
李莎莎
刘琪琪
李晔
张红
CHEN Jing;LIU Yang;ZHI Wenbing;AN Yuye;LI Shasha;LIU Qiqi;LI Ye;ZHANG Hong(School of Pharmacy,Shaanxi University of Traditional ChineseMedicine,Xianyang 712046,China;Shaanxi Academy of Traditional Chinese Medicine,Xi’an 710003,China)
出处
《特产研究》
2023年第1期162-173,179,共13页
Special Wild Economic Animal and Plant Research
基金
陕西省重点研发计划项目(No.2022ZDXM-SF-06,No.2021ZDLSF04-06)
陕西省中医药管理局“秦药”开发重点科学研究项目(No.2021-02-ZZ-002,No.2021-02-GJ-021)
陕西省中医药研究院2021年度院级“苗圃培育计划”项目(No.2021-13、No.2021-16)。
关键词
苦豆子
化学成分
药理作用
毒性
Sophora alopecuroides
chemical component
pharmacological effect
toxicity
