摘要
目的:分析月经不调患者应用逍遥丸联合四物汤治疗的效果及安全性。方法:选取华安县妇幼保健院妇科门诊部2020年1月—2021年12月收治的100例月经不调患者,按随机数表法分为两组,各50例。对照组采用四物汤治疗,观察组采用逍遥丸联合四物汤治疗。对比两组治疗效果、中医症候评分、血液流变学、性激素水平及不良反应等。结果:观察组总有效率为98.00%,高于对照组的82.00%(P<0.05)。治疗后,两组中医症候评分、血液流变学、性激素水平较治疗前均改善,且观察组经期不定、量多或少、淋漓不畅评分均低于对照组,高切、低切全血黏度及血浆黏度低于对照组,卵泡刺激素(FSH)、黄体生成素(LH)、催乳素(PRL)低于对照组,雌二醇(E2)、孕酮(P)水平均高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:逍遥丸联合四物汤治疗月经不调取得较好效果,可明显改善患者血液流变学及血清性激素水平。
Objective:To analyze the efficacy and safety of Xiaoyao Pills combined with Siwu Decoction in the treatment of patients with irregular menstruation.Method:A total of 100 patients with irregular menstruation who admitted to the Outpatient Department of Hua’an County Maternal and Child Health Center from January 2020 to December 2021 were selected and divided into two groups according to the random number table method,50 patients in each group.The control group was treated with Siwu Decoction treatment,the observation group was treated with Xiaoyao Pills combined with Siwu Decoction treatment.The therapeutic effect,traditional Chinese medicine(TCM)symptoms score,hemorheology,sex hormone levels and adverse reaction were compared between two groups.Result:The total effective rate of the observation group was 98.00%,which was higher than 82.00%of the control group(P<0.05).After treatment,the TCM symptom score,hemorheology and sex hormone levels of two groups were improved compared with those before treatment,the scores of irregular menstruation,more or less volume and dripping poor of the observation group were lower than those of the control group,the whole blood viscosity of high shear and low shear,plasma viscosity were lower than those of the control group,the levels of follicle-stimulating hormone(FSH),luteinizing hormone(LH)and prolactin(PRL)were lower than those of the control group,and the levels of estradiol(E2)and progesterone(P)were higher than those of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between two groups(P>0.05).Conclusion:Xiaoyao Pills combined with Siwu Decoction has a good effect in the treatment of irregular menstruation,and can significantly improve the blood rheology and serum sex hormone levels.
作者
陈燕珠
CHEN Yanzhu(Hua’an County Maternal and Child Health Center,Hua’an 363800,China)
出处
《中外医学研究》
2023年第3期53-57,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
逍遥丸
四物汤
月经不调
Xiaoyao Pills
Siwu Decoction
Irregular menstruation
