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新型降糖药及运动对2型糖尿病患者心血管的影响 被引量:1

Influence of new hypoglycemic agents and exercise on cardiovascular function in patients with type 2 diabetes mellitus
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摘要 心血管疾病(CVD)是2型糖尿病(T2DM)的常见及主要并发症,目前的新型降糖药:胰高血糖素样肽-1受体激动剂(GLP-1ARs)和钠葡萄糖转运体2(SGLT2)抑制剂可以有效地控制血糖,降低发生低血糖的风险,减少心血管事件的发生。运动处方治疗可以减轻T2DM患者的心血管负担,长期高强度间歇训练(HIIT)结合运动后补充蛋白质,可以改善心脏代谢情况。本文就GLP-1ARs、SGLT2抑制剂及HIIT对T2DM患者心血管的影响作一综述。 Cardiovascular diseases(CVD) is a frequent and major complication of type 2 diabetes mellitus(T2DM). Currently, novel hypoglycemic agents--glucagon-like peptide-1 receptor agonists(GLP-1ARs) and sodium-glucose transporter 2(SGLT2) inhibitors, can effectively control blood glucose, reduce risk of hypoglycemia and occurrence of cardiovascular events. Exercise prescription therapy can reduce cardiovascular burden in T2DM patients. Long-term high intensity interval training(HIIT) combined with protein supplementation after exercise can improve cardiometabolic status. The present article makes a review on influence of GLP-1ARs, SGLT2 inhibitors and HIIT on cardiovascular function in T2DM patients.
作者 徐阳 项莹 XU Yang;XIANG Ying(Department of Endocrinology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150081,China)
出处 《心血管康复医学杂志》 CAS 2023年第1期89-93,共5页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 心血管疾病 糖尿病 2型 钠-葡萄糖转运体2 Cardiovascular diseases Diabetes mellitus type 2 Sodium-glucose transporter 2
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