摘要
中性粒细胞(polymorphonuclear leukocytes,PMN)作为天然免疫系统抵御入侵微生物的第一道防线,当病原入侵机体时,最先迁移到感染部位,并通过吞噬、脱颗粒和分泌抗菌因子、产生活性氧(reactive oxygen species,ROS)及释放中性粒细胞胞外诱捕网(neutrophil extracellular traps,NETs)发挥其抗炎作用[1]。在保护宿主不受病原体侵害的同时,PMN不可避免的会损伤到宿主的细胞和组织,启动炎症和免疫反应,直接导致组织损伤和慢性炎症的进展[2]。
作者
石多美(综述)
唐雪梅(审校)
Shi Duomei;Tang Xuemei(Children’s Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,National Clinical Research Center for Child Health and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Child Infection and Immunity,Chongqing 400014,China)
出处
《儿科药学杂志》
CAS
2023年第2期61-64,共4页
Journal of Pediatric Pharmacy
