摘要
目的分析老年患者骨折及其预后的危险因素。方法回顾性分析2019年1月—2021年12月复旦大学附属华山医院静安分院收治的老年患者相关资料。通过倾向评分匹配法匹配患者,根据入院前有无骨折史分为骨折组(n=140)和未骨折组(n=140)。记录受试者的年龄、性别、共患病数、血清白蛋白(ALB)、血红蛋白(Hb)、血钙、血尿酸;明确受试者是否存在糖尿病、高脂血症、肝功能异常、肾功能异常。以受试者出院状态(死亡或存活)作为最终结局,分析患者骨折及死亡的危险因素。结果与未骨折组比较,骨折组共患病数较多,ALB和血钙水平较低,预后较差,差异有统计学意义(P<0.05)。Logistic回归分析显示,共患病数多(OR=1.281,P=0.018,95%CI:1.044~1.571)和低ALB(OR=1.051,P=0.045,95%CI:1.001~1.103)是老年患者发生骨折的危险因素。低血钙(OR=74.878,P=0.006,95%CI:1.238~7.393)以及低Hb(OR=1.058,P=0.004,95%CI:1.018~1.099)是老年骨折患者死亡的危险因素。结论共患病数多和低ALB可能是老年患者发生骨折的危险因素,而低血钙及低Hb可能是老年骨折患者死亡的危险因素。
Objective To analyze the risk factors for fracture and prognosis in elderly patients.Methods The data of elderly patients admitted to Jing’an Branch of Huashan Hospital Affiliated to Fudan University from January 2019 to December 2021 were retrospectively analyzed.Patients were matched by propensity score matching method and divided into fracture group(n=140)and non-fracture group(n=140)according to the history of fracture before admission.The age,sex,number of comorbidities and the levels of serum albumin(ALB),hemoglobin(Hb),blood calcium and blood uric acid of the patients were recorded.It was determined whether the patients had diabetes,hyperlipidemia,abnormal liver function and abnormal kidney function.The discharge status(death or survival)of patients was used as the final outcome,and the risk factors for fracture and death were analyzed.Results Compared with the non-fracture group,the fracture group had more comorbidities,lower levels of ALB and blood calcium,and poorer prognosis,with a statistically significant difference(P<0.05).Logistic regression analysis showed that more comorbidities(OR=1.281,P=0.018,95%CI:1.044-1.571)and low ALB(OR=1.051,P=0.045,95%CI:1.001-1.103)were risk factors for fracture in elderly patients;hypocalcemia(OR=74.878,P=0.006,95%CI:1.238-7.393)and low Hb(OR=1.058,P=0.004,95%CI:1.018-1.099)were risk factors for death in elderly patients with fracture.Conclusion More comorbidities and low ALB may be risk factors for fracture in elderly patients,while hypocalcaemia and low Hb may be risk factors for death in elderly patients with fracture.
作者
刘迟
唐韵
姜俊
王志安
Liu Chi;Tang Yun;Jiang Jun;Wang Zhi an(Department of Emergency,Jing'an Branch of Huashan Hospital Affiliated to Fudan University,Shanghai,20040,P.R.China)
出处
《老年医学与保健》
CAS
2023年第1期39-42,共4页
Geriatrics & Health Care
基金
国家重点研发计划(2018YFC2002400)。
关键词
老年
骨折
预后
危险因素
elderly
fracture
prognosis
risk factor
