摘要
目的探讨肺泡动脉氧分压差[difference of alveolar arterial oxygen partial pressure,P(A-a)O_(2)]应用于急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)的临床意义。方法回顾性分析2021年1月至2021年12月入住锦州医科大学附属第一医院重症医学科(intensive care unit,ICU)ARDS患者患者109例,收集患者入ICU即刻、24 h、48 h、72 h的氧合指数与P(A-a)O_(2),以及28 d的预后情况。根据28 d的预后结果将患者分为存活组(89例)与死亡组(20例),比较两组患者的各时间点的氧合指数与P(A-a)O_(2),并分析二者的相关性。结果两组患者入ICU各时间点的氧合指数与P(A-a)O_(2)差异均具有统计学意义(P<0.05);两组患者的氧合指数与P(A-a)O_(2)的呈明显负相关(P<0.05)。结论P(A-a)O_(2)有助于临床上对ARDS的病情与治疗效果进行判断。
Objective To explore the clinical significance of alveolar arterial oxygen partial pressure[P(A-a)O_(2)]in acute respiratory distress syndrome(ARDS).Methods A retrospective analysis was made on 109 ARDS patients admitted to intensive care unit(ICU)of the First Affiliated Hospital of Jinzhou Medical University from January 2021 to December 2021.The oxygenation index and P(A-a)O_(2)of the patients immediately,24h,48h and 72h after admission to ICU were collected,as well as the prognosis of 28d.The patients were divided into survival group(89 cases)and death group(20 cases)according to the prognosis results of 28 days.The oxygenation index and P(A-a)O_(2)at each time point of the two groups were compared,and the correlation between the two groups was analyzed.Results There was significant difference in oxygenation index and P(A-a)O_(2)between the two groups at each time point of admission to ICU(P<0.05);there was a significant negative correlation between the oxygenation index and P(A-a)O_(2)in the two groups(P<0.05).Conclusion P(A-a)O_(2)is helpful to judge the clinical condition and treatment effect of ARDS.
作者
郭闯
陈凤敏
储蕴
付海燕
Guo Chuang;Chen Fengmin;Chu Yun;Fu Haiyan(The First Affiliated Hospital of Jinzhou Medical University,Jinzhou 121000 China)
出处
《锦州医科大学学报》
2023年第1期38-41,共4页
Journal of Jinzhou Medical University
关键词
肺泡动脉氧分压差
氧合指数
急性呼吸窘迫综合征
回顾性分析
difference of alveolar arterial oxygen partial pressure
oxygenation index
acute respiratory distress syndrome
retrospective analysis
