期刊文献+

急诊首次肌钙蛋白Ⅰ联合GRACE评分在快速评估可疑心肌梗死病人中的作用

下载PDF
导出
摘要 目的:探讨急诊首次肌钙蛋白Ⅰ(cTnⅠ)联合GRACE评分对急诊胸痛病人可疑急性心肌梗死(AMI)的预测效果。方法:选取因胸痛于急诊内科就诊的237例病人,病人入院24 h内分别单独应用cTnⅠ水平、GRACE评分及两者联合方法进行AMI风险评估,比较cTnⅠ水平、GRACE评分及两者联合方法对急诊胸痛病人发生AMI的预测价值。结果:发生AMI病人104例,非AMI病人133例,AMI组吸烟史、高血压、糖尿病比例,以及cTnⅠ、GRACE评分均高于非AMI组(P<0.05~P<0.01)。cTnⅠ对急诊胸痛病人发生AMI预测的最佳切入点为1.105μg/L,灵敏度为86.5%,特异度为82.0%,约登指数为0.685,ROC曲线下面积为0.901[95%CI(0.860~0.942)];GRACE评分的最佳切入点为122分,灵敏度为76.9%,特异度为83.5%,约登指数为0.604,ROC曲线下面积为0.795[95%CI(0.735~0.856)];两者联合检测的灵敏度为89.4%,特异度为82.7%,约登指数为0.721,ROC曲线下面积为0.929[95%CI(0.897~0.961)]。结论:临床护理人员通过GRACE评分联合cTnⅠ的评估方式有助于早期识别急诊低危胸痛病人,筛查高危AMI病人,预测效果较好。
出处 《蚌埠医学院学报》 CAS 2023年第2期236-238,245,共4页 Journal of Bengbu Medical College
  • 相关文献

参考文献9

二级参考文献61

  • 1Chong CP, Lim WK, Velkoska E, et al. N -terminal pro -brain natriuretie peptide and angiotensin - converting enzyme - 2 levels and their association with postoperative cardiac complications after emergency orthopedic surgery[J]. Am J Cardiol, 2012, 109(9): 1365 - 1373.
  • 2James L, Januzzi AA, Chen -Tournoux G, et al. Amino -terminal pro -B -type natriuretic peptide testing for the diagnosis or exclu- sion of heart failure in patients with acute symptoms[ J]. Am J Car- diol, 2008, lOl(3A) : 29 -38.
  • 3Michtalik HI, Hsin CY, Catherine YC, et al. Acute changes in N - terminal pro - B - type natriuretic peptide during hospitalization and risk of readmission and mortality in patients with heart failure [ J ]. Am J Cardiol, 2011, 107(8): 1191-1195.
  • 4Collins SP, Pang PS, Butler J, et al. Revisiting cardiac injury dur- ing acute heart failure : further characterization and a possible target for therapy [ J ]. Am J Cardiol, 2015, 115 ( 1 ) : 141 - 146.
  • 5Pastormerlo LE, Agazio A, Benelli E, et al. Usefulness of high - sensitive troponin elevation after effort stress to unveil vulnerable myocardium in patients with heart failure [J]. Am J Cardiol, 2015, 116(4): 567-572.
  • 6Carol PC, Wen KL, Elena V, et al. N - terminal pro - brain natri- uretie peptide and angiotensin - converting enzyme - 2 levels and their association with postoperative cardiac complications after emer- gency orthopedic surgery[J]. Am J Cardiol, 2012, 109(9) - 1365 - 1373.
  • 7Krista CB, Christopher R, Robert HC, et al. Predictive value of depressive symptoms and B - type natriuretic peptide for new - on- set heart failure and mortality[J]. Am J Cardiol, 2011, 107(5) : 723 - 729.
  • 8Mitchell A, Misialek JR, Fo|som AR, et al. Usefulness of N - ter- minal pro- brain natriuretic peptide and myocardial perfusion in a- symptomatic adults (from the multi - ethnic study of atherosclero- sis) [ J]. Am J Cardiol, 2015, 115 (10) : 1341 - 1345.
  • 9Lindberg S, Jensen JS, Hoffmann S, et al. Interplay between adi- ponectin and pro -atrial natriuretic peptide and prognosis in pa- tients with ST - segment elevation myocardial infarction [ J ]. Am J Cardiol, 2015, 116(9) : 1340-1345.
  • 10无.急性ST段抬高型心肌梗死诊断和治疗指南[J].中华心血管病杂志,2010,38(8):675-690. 被引量:1947

共引文献399

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部