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白细胞计数、中性粒细胞与淋巴细胞比值联合红细胞沉降率、C反应蛋白在病毒性肺炎与细菌性肺炎诊断鉴别中的应用价值 被引量:8

Application value of white blood cell count,neutrophil to lymphocyte ratio combined with erythrocyte sedimentation rate and C-reactive protein in the diagnostic differentiation of viral pneumonia and bacterial pneumonia
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摘要 目的研究白细胞计数(WBC)、中性粒细胞与淋巴细胞比值(NLR)联合红细胞沉降率(ESR)、C反应蛋白(CRP)在病毒性肺炎与细菌性肺炎诊断鉴别中的应用价值。方法选取2019年2月至2021年12月安徽省第二人民医院54例病毒性肺炎(病毒组)、54例细菌性肺炎(细菌组)作为研究对象。比较两组血小板(PLT)、平均血小板体积(MVP)、WBC、N、L、NLR、ESR、CRP水平;分析WBC、NLR联合ESR、CRP检测对细菌性肺炎的诊断效能。结果细菌组WBC、N、NLR高于病毒组(P<0.05);两组PLT、MPV、L比较,差异无统计学意义(P>0.05)。细菌组ESR、CRP水平高于病毒组(P<0.05)。联合检测的曲线下面积高于各项单一检测(P<0.05)。结论WBC、NLR联合ESR、CRP检测能准确鉴别病毒性肺炎与细菌性肺炎,应用价值较高。 Objective To investigate the application value of white blood cell count(WBC),neutrophil to lymphocyte ratio(NLR)combined with erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)in the diagnostic differentiation of viral pneumonia and bacterial pneumonia.Methods A total of 54 cases of viral pneumonia(viral group)and 54 cases of bacterial pneumonia(bacterial group)in Anhui No.2 Provincial People’s Hospital from February 2019 to December 2021 were selected as research objects.Blood routine(PLT),mean platelet volume(MVP),WBC,N,L,NLR,ESR,and CRP were compared between two groups,and the diagnostic efficacy of WBC,NLR combined with ESR and CRP in bacterial pneumonia were analyzed.Results WBC,N,and NLR in bacterial group were higher than those in virus group(P<0.05);there were no significant difference in PLT,MPV,and L between two groups(P>0.05).The levels of ESR and CRP in bacterial group were higher than those in virus group(P<0.05).The area under the curve of combined detection was higher than that of single detection(P<0.05).Conclusion WBC,NLR combined with ESR and CRP can accurately distinguish viral pneumonia from bacterial pneumonia,and has high application value.
作者 汪平 罗兵 孙静茹 WANG Ping;LUO Bing;SUN Jingru(Department of Clinical Laboratory,Anhui No.2 Provincial People’s Hospital,Anhui Province,Hefei230012,China)
出处 《中国医药导报》 CAS 2023年第4期160-163,共4页 China Medical Herald
基金 安徽省教育厅自然科学研究重点项目(KJ2019A 1099)。
关键词 病毒性肺炎 细菌性肺炎 诊断鉴别 血常规 红细胞沉降率 C反应蛋白 Viral pneumonia Bacterial pneumonia Diagnostic differentiation Routine blood Erythrocyte sedimentation rate C-reactive protein
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