摘要
目的探讨无创机械通气在老年肺动脉高压呼吸衰竭患者中的应用效果。方法选取2019年10月—2020年11月本科室收入的68例肺动脉高压致呼吸衰竭患者为研究对象,采取奇偶法原则将其分为对照组和观察组,每组各34例。对照组采用有创机械通气,观察组采用无创机械通气,比较两组的治疗效果、血气分析、氧合指数、炎性因子及并发症发生率。结果治疗后,观察组治疗有效率高于对照组,并发症发生率低于对照组,两组比较差异均有统计学意义(χ^(2)=6.275、5.314,均P<0.05);PaCO_(2)、内皮素-1、白介素-6、C反应蛋白均低于对照组,PaO_(2)、SaO_(2)、氧合指数、BNP均高于对照组,两组比较差异均有统计学意义(t=5.902、4.484、10.555、6.436、2.534、3.662、8.513、30.181,均P<0.05)。结论老年肺动脉高压呼吸衰竭采取无创机械通气诊疗效果理想,可改善氧合功能,削弱炎性因子表达,亦可纠正血气指标,提高脑钠肽水平,并发症少、安全有效,值得推广。
Objective To investigate the effect of noninvasive mechanical ventilation in elderly patients with pulmonary hypertension and respiratory failure.Methods A total of 68 patients with pulmonary arterial hypertension induced respiratory failure admitted to our department from October 2019 to November 2020 were selected as the research objects and divided into control group and observation group by the principle of parity method,with 34 cases in each group.Invasive mechanical ventilation was used in the control group and non-invasive mechanical ventilation was used in the observation group.The therapeutic effects,blood gas analysis,oxygenation index,inflammatory factors and incidence of complications were compared between the two groups.Results After treatment,the effective rate of the observation group was higher than that of the control group,the complication rate was lower than that of the control group,the difference between the two groups was statistically significant(χ^(2)=6.275,5.314,all P<0.05).PaCO_(2),endothelin-1,interleukin-6 and C-reactive protein were all lower than control group,while PaO_(2),SaO_(2),oxygenation index and BNP were all higher than those of the control group.The differences between the two groups were statistically significant(t=5.902,4.484,10.555,6.436,2.534,3.662,8.513,30.181,all P<0.05).Conclusion Non-invasive mechanical ventilation is ideal for the diagnosis and treatment of elderly pulmonary arterial hypertension and respiratory failure.It can improve the oxygenation function,weaken the expression of inflammatory factors,correct the blood gas index,and increase the level of brain natriuretic peptide.It has fewer complications,is safe and effective,and is worthy of promotion.
作者
王虹
WANG Hong(Department of Respiratory,Bayannur Hospital,Bayannaoer,Inner Mongolia,O15000,China)
出处
《中国冶金工业医学杂志》
2023年第1期4-6,共3页
Chinese Medical Journal of Metallurgical industry
关键词
老年肺动脉高压
呼吸衰竭
无创机械通气
并发症
效果
Elderly pulmonary hypertension
Respiratory failure
Non-invasive mechanical ventilation
Complications
Effect
