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器官移植感染的精准快速实验诊断 被引量:1

Accurate and rapid experimental diagnosis of infection in organ transplantation
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摘要 尽管在手术技术、移植后护理、医院环境、免疫抑制、感染性疾病治疗、感染预防和移植受者预防方面取得了进展,但移植后感染仍是移植失败和患者死亡的主要原因[1]。以肝移植(liver transplantation,LT)为例,术后细菌感染是最常见的感染类型,其次是真菌、病毒和原虫感染[2-3]。医院获得性病原体是流行病学暴露的主要致病微生物[4]。美国20世纪80年代至90年代期间主要移植中心报告细菌感染发病率为53%~56%[5-6]。在2005年的一份队列报告中显示,47%的患者发生了细菌感染[7]。Kim等[8]报告,患者第1个月的发病率为30.2%,整个随访期(平均672 d)为67.9%。其他研究报告,在术后前3个月,病死率为14.1%[9]。
作者 肖楠 赵秀英 Xiao Nan;Zhao Xiuying
出处 《实用器官移植电子杂志》 2023年第1期1-5,共5页 Practical Journal of Organ Transplantation(Electronic Version)
基金 北京市2020年培育计划(PX2020043)。
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  • 1Yang, Yi,Yan, Lu-Nan,Zhao, Ji-Chun,Ma, Yu-Kui,Huang, Bin,Li, Bo,Wen, Tian-Fu,Wang, Wen-Tao,Xu, Ming-Qing,Yang, Jia-Yin.Microsurgical reconstruction of hepatic artery in A-A LDLT:124 consecutive cases without HAT[J].World Journal of Gastroenterology,2010,16(21):2682-2688. 被引量:7
  • 2Fabian A Romero,Raymund R Razonable.在肝的感染移植接受者[J].World Journal of Hepatology,2011,3(4):83-92. 被引量:28
  • 3Li, Chuan,Wen, Tian-Fu,Yan, Lu-Nan,Li, Bo,Yang, Jia-Ying,Wang, Wen-Tao,Xu, Ming-Qing,Wei, Yong-Gang.Outcome of hepatocellular carcinoma treated by liver transplantation:comparison of living donor and deceased donor transplantation[J].Hepatobiliary & Pancreatic Diseases International,2010,9(4):366-369. 被引量:5
  • 4Masao Hashimoto,Yasuhiko Sugawara,Sumihito Tamura,Junichi Kaneko,Yuichi Matsui,Junichi Togashi,Masatoshi Makuuchi.Clostridium difficile-associated diarrhea after living donor liver transplantation[J].World Journal of Gastroenterology,2007,13(14):2072-2076. 被引量:2
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  • 6K. E. Doucette,M. Al‐Saif,N. Kneteman,L. Chui,G. J. Tyrrell,D. Kumar,A. Humar.Donor‐Derived Bacteremia in Liver Transplant Recipients Despite Antibiotic Prophylaxis[J].American Journal of Transplantation.2013(4)
  • 7Puneeta Tandon,Angela DeLisle,Jeffrey E. Topal,Guadalupe Garcia–Tsao.High Prevalence of Antibiotic-Resistant Bacterial Infections Among Patients With Cirrhosis at a US Liver Center[J].Clinical Gastroenterology and Hepatology.2012(11)
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