摘要
目的 观察并探讨ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)患者血清高敏C反应蛋白(High sensitivity C-reactive protein,hs-CRP)、内皮细胞微粒(Endothelial microparticles,EMPs)及血浆脂联素(Adipose tissue,APN)水平变化与其心电图QRS积分的相关性。方法 以本院收治的STEMI患者100例开展研究,依照直径狭窄高于150%的血管支数分组,单支病变为A组,双支病变为B组,三支病变为C组。比较三组血清hs-CRP、EMPs、APN水平及心电图QRS积分,且对各指标间相关性实施分析。结果 血清hs-CRP、EMPs、APN水平及心电图QRS积分C组最高,其次是B组,A组最低(P<0.05)。Pearson相关因素分析,心电图QRS积分和血清hs-CRP、EMPs、APN水平呈正相关(r=0.732、0.689、0.423,P<0.05)。结论 STEMI患者心电图QRS积分和血清hs-CRP、EMPs、APN水平呈正相关,还可充分评估STEMI患者冠脉病变严重程度。
Objective To observe and explore the serum high sensitivity C-reactive protein in patients with ST-segment elevation myocardial infarction(STEMI),Hs-CRP),Endothelial microparticles,EMPs)and plasma adiponectin(APN)levels and their correlation with QRS score of electrocardiogram.Methods 100 patients with STEMI were studied.According to the number of blood vessels with diameter stenosis higher than 150%,the single vessel lesions were group A,double vessel lesions were group B and three vessel lesions were group C.The levels of serum hs-CRP,EMPs,APN and QRS score of electrocardiogram were compared among the three groups,and the correlation among these indexes was analyzed.Results The levels of serum hs-CRP,EMPs,APN and QRS score of electrocardiogram were the highest in group C,followed by group B and group A(P<0.05).Pearson correlation factor analysis,The QRS score of ECG was positively correlated with the levels of serum hsCRP,EMPs and APN(r=0.732,0.689 and 0.423,all P<0.05).Conclusion The QRS score of ECG in STEMI patients is positively correlated with the levels of serum hs-CRP,EMPs and APN,which can fully evaluate the severity of coronary artery disease in STEMI patients.
作者
李俊霞
Li Junxia(Electrocardiogram Room of Luoyang New District People's Hospital,Luoyang 471000,China)
出处
《哈尔滨医药》
2023年第1期16-18,共3页
Harbin Medical Journal
