摘要
目的:了解2019年1月至2022年6月该院发热门诊药品使用量等方面的变化,对常用药品应用情况及趋势进行客观评价,为临床合理用药提供参考。方法:利用医院信息系统,回顾性统计2019年1月至2022年6月该院发热门诊常用药品及患者处方的相关数据,对常用药品的年销售量、年销售金额、用药频度(DDDs)及联合用药情况进行统计分析。结果:2019年1月至2022年6月该院发热门诊使用的药品中,口服西药中洛索洛芬钠片、左氧氟沙星片和对乙酰氨基酚缓释片用量较多,口服中成药中蓝芩口服液、金花清感颗粒和苏黄止咳胶囊用量较多;注射剂中,注射用头孢曲松用量最多,注射用头孢曲松与DDDs排序居前3位的西药联合应用情况远多于其与DDDs排序居前3位的中成药联合应用。各年龄段使用注射用头孢曲松的患者中,2020年和2021年随着年龄的增加,注射用头孢曲松与DDDs排序居前3位的西药联合应用占比逐渐升高;2022年1—6月,60~<75岁使用注射用头孢曲松的患者中,注射用头孢曲松与DDDs排序居前3位的西药联合应用占比最高。各年龄段使用注射用头孢曲松的患者中,<45岁患者中注射用头孢曲松与DDDs排序居前3位的中成药联合应用占比最高;随着年龄的增加,上述联合用药的占比逐渐降低。结论:该院发热门诊注射用头孢曲松与西药的联合应用基本合理,符合安全、有效、经济的用药原则。但注射用头孢曲松与中成药的联合应用情况并不理想,建议临床医师在药物治疗的过程中合理地联合使用药物,保证患者用药安全。
OBJECTIVE:To investigate the changes of drug usage in fever clinics of the hospital from Jan.2019 to Jun.2022,and to perform objective evaluation on the application situation and trend of common drugs,so as to provide reference for clinical rational medication.METHODS:Data related to commonly used drugs and patient prescriptions in fever clinics of the hospital from Jan.2019 to Jun.2022 were retrospectively collected by using the hospital information system,which was analyzed in terms of annual sales amount,annual consumption sum,defined daily dose system(DDDs)and drug combination.RESULTS:Among the drugs used in fever clinics of the hospital from Jan.2019 to Jun.2022,the dosage of oral western medicine was higher for Loxoprofen sodium tablets,Levofloxacin tablets and Acetaminophen sustained release tablets,the dosage of oral Chinese patent medicine was higher for Lanqin oral liquid,Jinhua Qinggan granules and Suhuang Zhike capsules;as for injections,the dosage of ceftriaxone for injection the most,and the top three DDDs of western medicine in drug combination with ceftriaxone for injection was much more than the top three DDDs of Chinese patent medicine in drug combination.Among the patients who used ceftriaxone for injection at different ages,the proportion of combined use of ceftriaxone for injection and top 3 western drugs ranked by DDDs gradually increased with the increase of age in 2020 and 2021;from Jan.to Jun.2022,among the patients aged 60 to<75 who used ceftriaxone for injection,the combination of ceftriaxone for injection and top 3 western drugs ranked by DDDs accounted for the highest proportion.Among the patients who used ceftriaxone for injection at different ages,the proportion of the combination of ceftriaxone for injection and top 3 Chinese patent medicine ranked by DDDs was the highest among the patients<45 years old;with the increase of age,the proportion of the above combined drugs gradually decreased.CONCLUSIONS:The combined application of ceftriaxone for injection with western medicine in department of fever clinic in this hospital is basically reasonable,which is in line with the medication principles of safe,effective and economical efficiency.However,the combined application of ceftriaxone for injection with Chinese patent medicine was unsatisfactory,and it is suggested that clinicians should reasonably combine drugs in the process of treatment to ensure medication safety for patients.
作者
于丹丹
崔婧
陈文倩
张翠翠
李朋梅
YU Dandan;CUI Jing;CHEN Wenqian;ZHANG Cuicui;LI Pengmei(Dept.of Pharmacy,China-Japan Friendship Hospital,Beijing 100029,China)
出处
《中国医院用药评价与分析》
2023年第2期237-240,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
发热门诊
合理用药
头孢曲松
联合用药
Fever clinic
Rational medication
Ceftriaxone
Drug combination
