摘要
【目的】检索并筛选胃肠恶性肿瘤患者术后行肠外营养治疗预防低血糖发生的相关循证方法。【方法】通过检索美国国立指南库、苏格兰校际指南网、乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)网站、Cochrane Library、PubMed、Web of Science、国际糖尿病联盟网站、维普、中国知网、万方数据库、医脉通、中国生物医学文献数据库中有关胃肠恶性肿瘤术后行肠外营养治疗中,预防低血糖发生的相关方法,包括指南、临床决策、证据总结、系统评价及专家共识。检索时限为2021年8月至12月,由2名研究者对文献质量进行独立评价,同时提取和汇总相关证据。【结果】共纳入文献11篇,包括2篇指南、6篇专家共识、1篇证据总结、2篇RCT论文,共总结了16条证据,内容包括术前评估、胰岛素加入方式、推荐剂量、血糖控制、建立血糖管理团队、血糖监测方案、肠外营养液的配置、围术期饮食指导8个方面。【结论】总结胃肠恶性肿瘤患者术后行肠外营养治疗预防低血糖发生的最佳循证方法较全面,可为降低胃肠恶性肿瘤患者术后行肠外营养治疗低血糖的发生率提供循证依据。
【Objective】To search and screen the relevant evidence-based methods for preventing hypoglycemia in patients with gastrointestinal malignant tumor undergoing parenteral nutrition after operation.【Methods】The US National Guide Library,Scottish Intercollegiate Guide Network,Joanna Briggs Institute(JBI)website,Cochrane Library,PubMed,Web of Science,International diabetes Alliance website,VIP,CNKI,Wanfang database,Yimaitong and Chinese biomedical literature database were searched in order to explore the relevant methods to prevent hypoglycemia during parenteral nutrition treatment after operation of gastrointestinal malignant tumor.These data include guidelines,clinical decision-making,evidence summary,systematic evaluation and expert consensus.The retrieval period was from August 2021 to December 2021.Two researchers independently evaluated the quality of the literature,and extracted and summarized relevant evidence at the same time.【Results】A total of 11 documents were included,including 2 guidelines,6 expert consensus,1 evidence summary,and 2 RCT papers.A total of 16 evidences were summarized,including 8 aspects,including preoperative evaluation,insulin addition method,recommended dose,blood glucose control,establishment of blood glucose management team,blood glucose monitoring program,parenteral nutrition solution configuration,and perioperative diet guidance.【Conclusion】It is comprehensive to summarize the best method to prevent hypoglycemia in patients with gastrointestinal malignant tumor after operation by parenteral nutrition,which can provide evidence basis for reducing the incidence of hypoglycemia in patients with gastrointestinal malignant tumor after operation by parenteral nutrition.
作者
朱菲
张灿芝
丁琼
陈明艳
胡伟
ZHU Fei;ZHANG Can-zhi;DING Qiong(Changsha Center Hospital,Changsha Hunan 410004)
出处
《医学临床研究》
CAS
2023年第2期261-264,共4页
Journal of Clinical Research
基金
南华大学附属长沙中心医院院级课题(YNKY202240)。
