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从络病理论认识肿瘤新生血管 被引量:8

Understanding of Tumor Neovascularization from Perspective of Collateral Disease Theory
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摘要 络病是络脉功能和(或)结构异常导致的病变,其亢盛的生成方式导致络脉滋生,无序迂曲的结构特点形成络脉瘀阻、络气亏虚,通透性高的功能特点是络气不固的重要表现。临证治疗肿瘤新生血管,应以虫类药平亢抑络,以辛味药辛散通络,以补气收涩药益气固络,从而破坏或者抑制肿瘤血管,降低其生成速度,减少肿瘤血管数量,达到改善微环境,降低肿瘤新生血管通透性的目的。 Collateral disease takes place based on collateral dysfunction.In other words, it is caused by the abnormal function and/or structure of collaterals.Its hyperactivity leads to the growth of collaterals and its disordered and tortuous structural characteristics form the stagnation of collaterals and the Qi deficiency of collaterals.The functional characteristics of high permeability are important manifestations of the dysfunction of collaterals.In the clinical treatment of tumor neovascularization, insect drugs should be used to calm the hyperactivity and inhibit the collaterals, pungent drugs should be used to disperse stagnation and dredge the collaterals, and drugs for invigorating Qi and astringent drugs should be used to replenish Qi and strengthen the collaterals, so as to destroy or inhibit tumor blood vessels, reduce their growth rate, reduce the number of tumor blood vessels, and improve the microenvironment and reduce the permeability of new blood vessels.
作者 王一然 李晶 WANG Yiran;LI Jing(Hebei Medical University,Shijiazhuang Hebei China 050011;The Fourth Hospital of Hebei Medical University,Shijiazhuang Hebei China 050011)
出处 《中医学报》 CAS 2023年第3期525-529,共5页 Acta Chinese Medicine
关键词 肿瘤新生血管 络病 络脉 平亢抑络 辛散通络 益气固络 tumor neovascularization collateral disease collateral calming hyperactivity and suppressing collaterals disperse stagnation and dredge the collaterals replenish Qi and strengthen collaterals
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