摘要
目的:探究快速康复外科(ERAS)对肝癌患者围手术期应激反应及术后胃肠功能恢复的影响。方法:选取2021年5月-2022年5月于南昌大学第二附属医院肝胆外科行肝癌切除手术的200例患者,按随机数字表法将其分为两组,各100例。对照组围手术期接受常规护理,ERAS组围手术期接受ERAS护理。比较两组术后恢复情况、住院费用、应激反应指标[C反应蛋白(CRP)、皮质醇(Cor)]及并发症情况。结果:ERAS组术后首次排气、拔除腹腔引流管时间、住院时间均较对照组短,住院费用较对照组少(P<0.05)。两组术后1、3 d的Cor、CRP水平均高于术前,且术后3 d的Cor、CRP水平均低于术后1 d(P<0.05)。ERAS组术后1、3 d的Cor、CRP水平均低于对照组(P<0.05)。ERAS组并发症总发生率较对照组低(P<0.05)。结论:肝癌患者采用ERAS可减轻其围手术期应激反应,加快其胃肠功能恢复,降低并发症发生率,减少住院费用。
Objective:To investigate the effect of enhanced recovery after surgery(ERAS)on perioperative stress response and postoperative gastrointestinal function recovery in patients with liver cancer.Method:A total of 200 patients who underwent liver cancer resection in the Department of Hepatobiliary Surgery of the Second Affiliated Hospital of Nanchang University from May 2021 to May 2022 were selected,they were divided into two groups according to the random number table method,with 100 cases in each group.The control group received routine nursing during the perioperative period,and the ERAS group received ERAS nursing during the perioperative period.The postoperative recovery,hospitalization costs,stress response indicators[C reactive protein(CRP),cortisol(Cor)]and complications were compared between the two groups.Result:The first postoperative exhaust,postoperative abdominal drainage tube removal time,hospital stay in the ERAS group were shorter than those in the control group,and hospitalization costs in the ERAS group was less than that in the control group(P<0.05).The levels of Cor and CRP at 1 and 3 d after surgery in both groups were higher than those before surgery,and the levels of Cor and CRP at 3 d after surgery were lower than those at 1 d after surgery(P<0.05).The levels of Cor and CRP in the ERAS group at 1 and 3 d after surgery were lower than those in control group(P<0.05).The overall incidence of complications in the ERAS group was lower than that in the control group(P<0.05).Conclusion:ERAS can reduce the perioperative stress response in patients with liver cancer,promote the recovery of postoperative gastrointestinal function,reduce the incidence of complications and the cost of hospitalization.
作者
谭巍
翁巧玲
TAN Wei;WENG Qiaoling(The Second Affiliated Hospital of Nanchang University,Nanchang 330006,China;不详)
出处
《中国医学创新》
CAS
2023年第6期94-97,共4页
Medical Innovation of China
基金
江西省卫生健康委科技计划项目(202210509)。
关键词
肝癌
快速康复外科
应激反应
胃肠功能
Liver cancer
Enhanced recovery after surgery
Stress response
Gastrointestinal function
