摘要
目的:探讨针刺治疗帕金森病合并强迫状态的疗效。方法:选取2021年1月—2022年6月在上海市浦东新区中医医院治疗的帕金森病合并强迫状态患者103例,将其随机分为针刺组(n=52)和西医组(n=51)。西医组:给予患者多巴丝肼片和盐酸舍曲林片治疗;针刺组:在西医组治疗方法基础上给予针刺治疗。比较两组临床症状[帕金森病统一评分量表(UPDRS)评分、YALE-BROWN强迫量表(YBCS)评分、汉密尔顿焦虑量表(HAMA)评分、汉密尔顿抑郁量表(HAMD)评分]、疗效及不良反应。结果:针刺组和西医组治疗后UPDRS、YBCS、HAMA、HAMD评分低于治疗前,针刺组治疗后UPDRS、YBCS、HAMA、HAMD评分低于西医组,差异有统计学意义(t值分别为3.779、3.180、6.200、5.483,P<0.05);针刺组强迫状态改善率、帕金森病治疗有效率高于西医组,差异有统计学意义(χ2值分别为4.118、4.471,P值均<0.05);针刺组和西医组不良反应率比较,差异无统计学意义(P>0.05)。结论:在西医治疗基础上,联合针刺治疗可改善帕金森病合并强迫状态患者临床症状,提高了疗效,且安全性好,具有应用价值。
OBJECTIVE To discuss the effect of acupuncture on Parkinson’s disease(PD)with obsessive state.METHODS A total of 100 patients with PD with obsessive state in our hospital from January 2021 to June 2022 were selected,and they were randomly divided into acupuncture group(n=52)and Western medicine(WM)group(n=51).The WM group was given sertraline hydrochloride tablets and doserhydrazine tablets treatment,and the acupuncture group was given acupuncture on this basis,the clinical symptoms[PD Unified Scoring Scale(UPDRS),Yale-Brown Obsessive Compulsive Scale(YBCS)and Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD)],efficacy and adverse reactions were compared.RESULTS The UPDRS,YBCS,HAMA and HAMD scores after treatment in acupuncture group and WM group were lower than those in the before treatment,the UPDRS,YBCS,HAMA and HAMD scores in acupuncture group after treatment were lower than those in WM group(t=3.779,3.180,6.200,5.483,P<0.05).The improvement rate of obsessive state and effective rate of PD in acupuncture group were higher than those in WM group(χ~2=4.118,4.471,P<0.05).The adverse reaction rate was similar in acupuncture group and WM group(P>0.05).CONCLUSION On the basis of western medicine treatment,combined acupuncture treatment can improve the clinical symptoms of patients with Parkinson’s disease combined with compulsive state,improve the curative effect,and have good safety and application value.
作者
顾竞
沈利荣
沈丽萍
王萍
陈雪莲
许佩佩
姚晓庆
王厹东
GU Jing;SHEN Li-rong;SHEN Li-ping;WANG Ping;CHEN Xue-lian;XU Pei-pei;YAO Xiao-qing;WANG Qiu-dong(Shanghai Pudong New Area Hospital of Traditional Chinese Medicine,Shanghai,201200,China)
出处
《中国初级卫生保健》
2023年第2期89-91,共3页
Chinese Primary Health Care
基金
上海市卫生健康委员会项目(202040115)。
关键词
针刺
帕金森病
强迫状态
疗效
不良反应
acupuncture therapy
Parkinson’s disease
obsessive state
efficacy
adverse effect
