摘要
目的探讨水囊联合利凡诺用于中期妊娠引产的临床效果及安全性。方法选取58例中期妊娠引产孕妇,依据随机数字表法分为对照组与研究组,每组29例。对照组实施羊膜腔内注射利凡诺引产,研究组实施水囊联合利凡诺引产,两组用药后均观察24 h。比较两组临床疗效。结果用药后,研究组临床引产总有效率96.55%高于对照组的72.41%,差异有统计学意义(P<0.05)。研究组引产时间、引产至胎儿及胎盘娩出时间短于对照组,引产成功率高于对照组,差异有统计学意义(P<0.05)。研究组产后清宫率低于对照组,差异有统计学意义(P<0.05)。与用药前比较,用药后两组宫颈黏液前列腺素E2(PGE2)、前列腺素F2α(PGF2α)表达水平均升高,且研究组高于对照组,差异有统计学意义(P<0.05)。结论水囊联合利凡诺应用于中期妊娠引产可有效提高引产成功率,降低产后清宫率,促进宫颈成熟,安全性高,临床效果显著。
Objective To investigate the clinical effect and safety of water capsule combined with Rivanol in inducing labor during second trimester.Methods 58 pregnant women with second trimester induced labor were selected and divided into control group and study group according to random number table method,with 29 cases in each group.The control group received intramniotic injection of rivanol for induction of labor,while the study group received water capsule combined with rivanol for induction of labor.Both groups were observed for 24 h after medication.The clinical efficacy of the two groups was compared.Results After medication,the total effective rate of clinical labor induction in the study group was 96.55% higher than that in the control group 72.41%,the difference was statistically significant(P<0.05).The time of labor induction,labor induction to fetal and placenta delivery in the study group was shorter than that in the control group,and the success rate of labor induction was higher,the difference was statistically signifi cant(P<0.05).The postpartum clearance rate of the research group was lower than that of the control group,and the difference was statistically significant(P<0.05).Compared with before treatment,the expression levels of cervical mucus prostaglandin E2(PGE2)and prostaglandin F2α(PGF2α)in two groups were increased after treatment,and the study group was higher than the control group,the difference was statistically signifi cant(P<0.05).Conclusion The application of water capsule combined with rivanol in the induction of labor in the second trimester of pregnancy can effectively improve the success rate of labor induction,reduce the rate of postpartum cesarean clearance,and promote the maturity of the cervix,with high safety and signifi cant clinical effect.
作者
刘霞
彭巧珍
Liu Xia;Peng Qiaozhen(Department of Obstetrics,Xiangtan County People's Hospital,Xiangtan 411228,China;Department of Obstetrics,XiangyaHospital of Central South University,Changsha 410008,China)
出处
《实用妇科内分泌电子杂志》
2022年第29期59-61,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
中期妊娠引产
水囊
利凡诺
Labor induction in the second trimester of pregnancy
Water capsule
Rivanol
