摘要
目的本研究旨在从血清生化标志物层面探讨影响不同性别中年体检人群非酒精性脂肪肝(NAFLD)的相关影响因素。方法选取2021年3月-2022年3月在平凉市某二级甲等医院体检的460例中年人群作为研究对象,收集中年体检人群的一般资料、体质量指数、血压及血清生化标志物水平,采用单因素及多因素Logistic回归探讨影响中年体检人群非酒精性脂肪肝发生的血清生化标志物。结果460例研究对象中137例患NAFLD,患病率为31.5%。Logistic回归显示,体质量指数、空腹血糖、甘油三酯、尿酸是中年男性人群非酒精性脂肪肝的危险因素,年龄、高密度脂蛋白胆固醇是中年男性体检人群非酒精性脂肪肝的保护因素(P<0.05)。体质量指数、血红蛋白、空腹血糖、甘油三酯是中年女性体检人群非酒精性脂肪肝的危险因素(P<0.05)。结论平凉市中年体检人群非酒精性脂肪肝患病情况需要引起重视,尤其注意控制体质量指数、空腹血糖及甘油三酯,同时应当大力发展初级医疗保健筛查,提高自我筛查意识,维护人群整体健康。
ObjectiveThis study aimed to explore the relevant factors affecting nonalcoholic fatty liver disease(NAFLD)in middle-aged people of the different sexes from the level of serum biochemical markers.MethodsA total of 460 middle-aged people who underwent physical examination in a secondary care hospital from March 2021 to March 2022 were selected as the study subjects,and collected the general data,body mass index,blood pressure and serum biochemical markers of middle-aged people.Univariate and multivariate Logistic regression were used to investigate the serum biochemical markers affecting the occurrence of nonalcoholic fatty liver disease in middle-aged physical examination population.ResultsAmong the 460 subjects,137 had NAFLD,the prevalence was 31.5%.Logistic regression showed that body mass index,fasting blood glucose,triglyceride uric acid and glutamine transpeptidase were risk factors for nonalcoholic fatty liver disease in the male middle-aged physical examination population.Age and high-density lipoprotein cholesterol was a protective factor of nonalcoholic fatty liver disease in male middle-aged physical examination population(P<0.05),and body mass index,hemoglobin,fasting blood glucose and triglyceride were risk factors of nonalcoholic fatty liver disease in female middle-aged physical examination population(P<0.05).ConclusionThe prevalence of nonalcoholic fatty liver disease in the middle-aged physical examination population in Pingliang should be paid attention to,especially the control of body mass index,fasting blood sugar and triglycerides.At the same time,it should vigorously develop primary medical care screening,improve self-screening awareness and maintain overall health.
作者
咸亚静
王仁媛
蔡雯
马丽荣
林素兰
XIAN Yajing;WANG Renyuan;CAI Wen;MA Lirong;LIN Sulan(College of Nursing,Xinjiang Medical University,Urumqi 830017;Gansu Pingliang Traditional Chinese Medicine Hospital,Pingliang Gansu 744000,China)
出处
《新疆医科大学学报》
CAS
2023年第2期254-258,共5页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区自然科学基金(2021D01C270)。
关键词
非酒精性脂肪肝
中年人群
高密度脂蛋白胆固醇
血红蛋白
non-alcoholic fatty liver disease
middle-aged population
high-density lipoprotein cholesterol
hemoglobin
