摘要
犬脾脏淋巴组织结节性增生(nodules of lymphoid hyperplasis,FHN)是较常见的犬脾脏肿大疾病,需借助组织病理学技术进行准确诊断。文章总结了两例不同分级的犬FHN,利用H.E.和免疫组织化学(immnohistochemistry,IHC)染色技术,标记CD3、CD19和Vimentin,结合其形态学特征,将其分别诊断为Ⅰ级和Ⅱ级FHN,并以脾脏肿块中淋巴细胞和其他基质细胞的相对比例为依据,为准确诊断犬脾脏FHN提供参考。
Nodules of lymphoid hyperplasis in canine spleen(FHN) is a common clinical disease and the disease needs to be diagnostics with the help of histopathology. In the article, two cases of canine FHN with different grades were reported.H.E. and immunohistochemical(IHC) staining techniques were used to diagnose. By marking CD3, CD19, Viementin, and combined with morphological characteristics, these two cases were diagnosed as Ⅰ grade and Ⅱ grade FHN. The differential diagnosis is based on the relative proportion of lymphocytes and other stromal cells in the splenic mass and this article would provided a reference for the accurate diagnosis of FHN in the spleen of canie.
作者
陈舒怀
吴晓星
吴波
孟雪
康桦
Chen Shuhuai;Wu Xiaoxing;Wu Bo;Meng Xue;Kang Hua(Zhejiang Institute For Drug Control,Zhejiang Hangzhou 310052;The Second Affiliated Hospital of Zhejiang University,Clinical Research Center,Zhejiang Hangzhou 310009)
出处
《现代畜牧兽医》
2023年第1期46-49,共4页
Modern Journal of Animal Husbandry and Veterinary Medicine
关键词
淋巴组织结节性增生
犬
分级
免疫组织化学
Nodules of lymphoid hyperplasis
Canine
Grade
Immnohistochemistry
