摘要
目的:探讨血脂代谢异常与急性胆源性胰腺炎(ABP)严重程度及其预后的相关性。方法:选取2017年1月—2021年12月苏州科技城医院收治的251例ABP患者为研究对象,根据甘油三酯(TG)水平分为正常TG组、轻度高TG组、中度高TG组。统计三组临床资料(年龄、性别、病史),病情严重度,Ranson评分,全身和局部并发症发生情况,分析血脂水平与ABP严重度的相关性和预后。结果:三组性别,伴有高血压、糖尿病、肥胖患者,平均住院时间比较,差异无统计学意义(P>0.05);轻度高TG组和中度高TG组平均发病年龄均低于正常TG组,差异有统计学意义(P<0.05);轻度高TG组与中度高TG组发病年龄比较,差异无统计学意义(P>0.05)。轻度高TG组和中度高TG组发生中度重症急性胰腺炎(MSAP)的发生率多于正常TG组,差异有统计学意义(P<0.05);轻度高TG组与中度高TG组MSAP的发生率比较,差异无统计学意义(P>0.05)。轻度高TG组与正常TG组重症急性胰腺炎(SAP)的发生率比较,差异无统计学意义(P>0.05);中度高TG组SAP的发生率多于正常TG组和轻度高TG组,差异有统计学意义(P<0.05)。中度高TG组轻症急性胰腺炎(MAP)的发生率少于正常TG组和轻度高TG组,轻度高TG组MAP的发生率少于正常TG组,差异有统计学意义(P<0.05)。轻度高TG组和中度高TG组Ranson评分高于正常TG组,差异有统计学意义(P<0.05);中度高TG组Ranson评分高于轻度高TG组,差异有统计学意义(P<0.05)。轻度高TG组、中度高TG组全身并发症和局部并发症的发生率高于正常TG组,差异有统计学意义(P<0.05)。结论:血脂代谢异常与ABP的严重程度有一定的相关性,与ABP的预后亦有相关性。
Objective:To explore the correlation between abnormal lipid metabolism and the severity and prognosis of acute biliary pancreatitis(ABP).Methods:A total of 251 ABP patients admitted to Suzhou Science and Technology Town Hospital from January 2017 to December 2021 were selected as the study subjects,and they were divided into normal TG group,mild high TG group,and moderate high TG group according to triglyceride(TG)levels.The clinical data(age,sex,past medical history),disease severity,Ranson score,systemic and local complications in three groups were analyzed,and the correlation between blood lipid level and ABP severity and prognosis was analyzed.Results:There was no significant difference in the average length of hospital stay of patients with hypertension,diabetes and obesity among the three groups(P>0.05).The mean age of onset was lower in the mild high TG group and the moderate high TG group than in the normal TG group,and the difference was statistically significant(P<0.05).There was no significant difference in age of onset between the mild high TG group and the moderate high TG group(P>0.05).The incidence of moderate severe acute pancreatitis(MSAP)in the mild high TG group and the moderate high TG group was higher than that in the normal TG group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of MSAP between the mild high TG group and the moderate high TG group(P>0.05).There was no significant difference in the incidence of severe acute pancreatitis(SAP)between the mild high TG group and the normal TG group(P>0.05).The incidence of SAP in the moderate high TG group was higher than that in the normal TG group and the mild high TG group,and the difference was statistically significant(P<0.05).The incidence of mild acute pancreatitis(MAP)in the moderate high TG group was lower than that in the normal TG group and the mild high TG group,and the incidence of MAP in the mild high TG group was lower than that in the normal TG group,and the difference was statistically significant(P<0.05).The Ranson score was higher in the mild high TG group and the moderate high TG group than in the normal TG group,and the difference was statistically significant(P<0.05).The Ranson score in the moderate high TG group was higher than that in the mild high TG group,and the difference was statistically significant(P<0.05).The incidence of systemic complications and local complications in the mild high TG group and the moderate high TG group was higher than that in the normal TG group,and the difference was statistically significant(P<0.05).Conclusion:Abnormal lipid metabolism has a correlation with ABP severity and ABP prognosis.
作者
刘杰
朱琪麟
王良晶
康刘敏
史肖华
Liu Jie;Zhu Qi-lin;Wang Liang-jing;Kang Liu-min;Shi Xiao-hua(Department of Gastroenterology,Suzhou Science and Technology Town Hospital,Suzhou 215153,Jiangsu Province,China)
出处
《中国社区医师》
2023年第7期41-43,共3页
Chinese Community Doctors
基金
江苏省苏州高新区医疗卫生科技计划青年科技项目(编号:2020Q010)
江苏省苏州高新区医疗卫生科技计划重点项目(编号:2020Z011)。
