摘要
彝族药蜘蛛香(Valeriana jatamansi Jones)中含有多种化学成分,主要为环烯醚萜类、挥发油类、木脂素类和黄酮类。据现代药学研究表明,蜘蛛香有多种药理作用,如中枢抑制作用、抗菌和抗病毒作用、细胞毒性和抗肿瘤作用等。本文基于中药质量标志物的概念,从蜘蛛香化学成分特有性、传统药效、传统药性、化学成分可测性等几个方面,对蜘蛛香的中药质量标志物成分进行预测分析,以期为蜘蛛香的质量控制和合理应用提供新思路。
The Yi medicine Valeriana jatamansi contains many chemical components,such as iridoids,volatile oils,lignans and flavonoids.According to modern pharmaceutical research,Valeriana jatamansi delivers a range of pharmacological effects,such as central inhibition,antibacterial and antiviral effects,cytotoxicity and anti-tumor effect.Based on the concept of Q-markers,this article predicted and analyzed the Q-marker components of Valeriana jatamansi in terms of specificity,traditional medicinal effects,traditional medicinal properties,and measurability of chemical constituents in the hopes of providing reference for quality control and rational use of Valeriana jatamansi.
作者
蔡于罗
果佳慧
王鑫国
田义龙
王梦
牛丽颖
李军山
CAI Yuluo;GUO Jiahui;Wang Xinguo;TIAN Yilong;WANG Meng;NIU Liying;LI Junshan(Hebei University of Chinese Medicine,Shijiazhuang Hebei 050091,China;Hebei TCM Formula Granule Innovation Center,Shijiazhuang Hebei 050091,China;Hebei TCM Quality Evaluation&Standardization Engineering Research Center,Shijiazhuang Hebei 050091,China;Shineway Pharmaceutical Group Ltd.,Shijiazhuang Hebei 051430,China)
出处
《中国药物警戒》
2023年第3期348-352,共5页
Chinese Journal of Pharmacovigilance
基金
中央引导地方科技发展资金项目(206Z2501G)
河北省重点研发计划(20372502D)
河北省自然科学基金资助项目(H2019423050)。
关键词
蜘蛛香
环烯醚萜
挥发油
药理作用
质量控制
质量标志物
Valeriana jatamansi
iridoids
volatile oils
pharmacological effects
quality control
quality marker
