摘要
目的探讨并分析妊娠期贫血患者血常规、铁代谢检查及网织红细胞参数检验结果的临床应用价值。方法选取我院2020年1月至2021年9月收治符合妊娠期贫血患者及健康孕妇对照组及非孕健康对照组,统计分析血常规、血清铁蛋白(SF)、血清铁(SI)、网织红细胞多参数间的差异。结果妊娠期贫血组血常规、网织红细胞、铁代谢指标与妊娠期健康组及正常对照组之间进行对比分析:血常规六项参数在妊娠贫血组、健康孕妇对照组、非孕健康对照组两两比较,3组间差异具有统计学意义(P<0.05),网织红细胞参数∶网织红细胞百分率(RET%)、网织红细胞绝对值(RET#)、未成熟网织红细胞比率(IRF%)、低荧光强度网织红细胞比率(LFR%)、中荧光强度网织红细胞比率(MFR%)、高荧光强度网织红细胞比率(HFR%)3组间比较差异具有统计学意义(P<0.05),铁代谢指标SI、SF 3组间比较差异具有统计学意义(P<0.05)。结论通过对妊娠期贫血患者的血常规、网织红细胞多参数与铁代谢多指标联合检测的比较分析,可早期诊断鉴别贫血,判断贫血程度并采取对应干预措施,减少因贫血导致的不良事件,保证母婴健康,在临床中具有重要意义。
Objective To investigate the profiles of blood routine test,reticulocytes and iron metabolism in patients with anemia during pregnancy and their usefulness in clinical setting.Methods Included in this study were patients admitted to our hospital who fulfilled the diagnostic criteria for anemia during pregnancy(anemic pregnancy group)between January 2020 and September 2021,as well as healthy pregnant women(non-anemic pregnancy group)and non-pregnant healthy women(healthy control group).The three groups were com-pared statistically for differences in profiles of blood routine test,serum ferritin(SF),serum iron(SI),and reticulocytes.Results Comparative analyses were performed on profiles of blood routine test,reticulocytes,and iron metabolism among the anemic pregnancy group,non-anemic pregnancy group and the healthy control group.The results showed statistical differences in profiles of the 6-item blood routine test panel across the anemic preg-nancy group,non-anemic pregnancy group and the healthy control group by between-group comparison(P<0.05),so were for the profiles of reticulocytes including the percentage count(RET%)and absolute value(RET#)of reticulocytes,immature reticulocyte fraction(IRF),and percentages of low fluorescence reticulocyte(LFR),medium fluorescence reticulocyte(MFR),and high fluorescence reticulocyte percentage(HFR)(P<0.05),and also for the profiles of iron metabolism including the SI and SF levels(P<0.05).Conclusion Combined testing and comparative analyses on profiles of blood routine test,reticulocytes,and iron metabolism among the anemic pregnant women may help early identification,diagnosis and severity assessment of the anemia,such that proper interventions can be accordingly practiced to reduce the anemia-related adverse events and ensure the health of mother and infant,which is of great significance in clinical practice.
作者
崔建健
乔小霞
陈雪
Cui Jianjian;Qiao Xiaoxia;Chen Xue(Department of Clinical Laboratory,Ningxia Hospital of Traditional Chinese Medicine and Institute of Traditional Chinese Medicine,Yingchuan750011,China)
出处
《实用医技杂志》
2022年第11期1171-1174,共4页
Journal of Practical Medical Techniques
关键词
贫血
网状细胞计数
妊娠并发症
Anenia
Reticulocyte count
Pregnancy complications
