摘要
目的:观察二陈汤合三子养亲汤联合西药治疗痰浊阻肺型慢性阻塞性肺疾病的临床疗效。方法:采用随机数字表法将98例痰浊阻肺型慢性阻塞性肺疾病患者分为对照组与治疗组各49例。对照组采用常规西药治疗,治疗组在对照组基础上给予二陈汤合三子养亲汤治疗。比较2组治疗前后中医证候评分、第1秒用力呼气容积(FEV_(1))、用力肺活量(FVC)、第1秒用力呼气容积与用力肺活量百分比(FEV_(1)/FVC)、世界卫生组织生存质量简表(QOL-BREF)评分,并评估2组临床疗效及不良反应发生情况。结果:治疗后,治疗组总有效率高于对照组(P<0.05)。治疗后,2组痰质、痰量、喘息、咳嗽中医证候评分均较治疗前降低(P<0.05),且治疗组治疗后中医证候评分低于对照组(P<0.05)。治疗后,2组FEV_(1)、FVC、FEV_(1)/FVC及QOLBREF评分均明显高于治疗前(P<0.05),且治疗组治疗后肺功能指标及QOL-BREF评分均高于对照组(P<0.05)。2组均未发生严重不良反应。结论:二陈汤合三子养亲汤联合西药治疗痰浊阻肺型慢性阻塞性肺疾病疗效确切,能有效改善患者肺功能,提高生活质量,安全性较高。
Objective:To observe the clinical effect of Erchen Decoction and Sanzi Yangqin Decoction combined with western medicine on chronic obstructive pulmonary disease(COPD) of phlegm turbidity obstructing the lung type. Methods:A total of 98 patients with COPD of phlegm turbidity obstructing the lung type were divided into the control group and the treatment group according to the random number table method, with 49 cases in each group. The control group was given routine western medicine, and the treatment group was additionally treated with Erchen Decoction and Sanzi Yangqin Decoction based on the treatment of the control group. Before and after treatment, the traditional Chinese medicine(TCM)syndrome scores,forced expiratory volume in one second(FEV_(1)),forced vital capacity(FVC) of expected value, percentage of FEV_(1)and FVC(FEV_(1)/FVC) and scores of World Health Organization Quality of LifeBrief Version(QOL-BREF) in the two groups were compared, and the clinical effects and incidence of adverse reactions were also evaluated. Results:After treatment,the total effective rate in the treatment group was higher than that in the control group(P<0.05). After treatment,the TCM syndrome scores of sputum quality, sputum volume, wheezing and cough in both groups were decreased when compared with those before treatment(P<0.05),and the above scores in the treatment group were lower than those in the control group(P<0.05). After treatment,the FEV_(1),FVC,FEV_(1)/FVC and QOL-BREF scores in the two groups were significantly higher than those before treatment(P<0.05), and the indexes of lung function and QOL-BREF scores in the treatment group were higher than those in the control group(P<0.05). No serious adverse reactions occurred in both groups. Conclusion: Erchen Decoction and Sanzi Yangqin Decoction combined with western medicine has a definite curative effect on COPD of phlegm turbidity obstructing the lung type,which can effectively improve the lung function of patients and enhance the quality of life,with good safety.
作者
吴建飞
李华
潘丹丹
滕少虹
周依娜
齐瑜
WU Jianfei;LI Hua;PAN Dandan;TENG Shaohong;ZHOU Yina;QI Yu
出处
《新中医》
CAS
2023年第5期68-71,共4页
New Chinese Medicine
关键词
慢性阻塞性肺疾病
痰浊阻肺
二陈汤
三子养亲汤
肺功能
生活质量
Chronic obstructive pulmonary disease
Phlegm turbidity obstructing the lung
Erchen Decoction
Sanzi Yangqin Decoction
Lung function
Quality of life
