摘要
作为一种广泛使用的结构单元,烯丙醇无需预官能化即可直接参与合成反应.近年来,烯丙醇的迁移反应得到了极大的关注,这类反应往往通过半频哪醇或neophyl重排等方式实现,为各种重要羰基化合物的合成提供了一种强有力的策略.系统综述了二芳基烯丙醇作为合成子时,涉及自由基引发基团迁移反应的最新进展,讨论了反应范围、局限性以及部分机理,并对该领域存在的挑战以及未来发展趋势进行展望.
As widely used building blocks,allyl alcohols can directly participate in the synthesis reaction without pre-functionalization.In recent years,the migration reaction of allyl alcohols has received great attention,and such reactions are often realized by semipinacol or neophyl rearrangement,providing a powerful strategy for the synthesis of various important carbonyl compounds.The latest progress of radical-initiated group migration reactions involving diaryl allyl alcohols as synthons systematically is reviewed,the scope,limitations and some mechanisms of the reaction are discussed,and the challenges and future development trends in this field are prospected.
作者
张建涛
邓雅文
莫诺琳
陈莲芬
Zhang Jiantao;Deng Yawen;Mo Nuolin;Chen Lianfen(College of Chemistry,Guangdong University of Petrochemical Technology,Maoming,Guangdong 525000;School of Environmental and Chemical Engineering,Zhaoqing University,Zhaoqing,Guangdong 526061)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2023年第2期426-435,共10页
Chinese Journal of Organic Chemistry
基金
广东石油化工学院人才引进计划(No.2019rc048)
国家自然科学基金(No.22002139)
广东省基础与应用基础研究基金(No.2019A1515110550)资助项目。
