摘要
目的:观察化瘀清络脑安汤结合脑栓通胶囊对急性期脑梗死患者肢体痉挛状态的影响。方法:采用前瞻性分析研究法,对2019年1月至2020年12月焦作市中医院脑病一区收治的急性期脑梗死患者120例进行研究,按照简单随机法分为观察组和对照组,各60例。对照组给予脑栓通胶囊治疗,观察组给予化瘀清络脑安汤结合脑栓通胶囊治疗。观察两组患者治疗前后中医证候积分、Ashworth量表评级、Fugl-Meyer运动功能评估量表(Fugl-Meyer assessment, FMA)评分、血液流变学指标[全血高切黏度、全血低切黏度、红细胞(red blood cell, RBC)压积、血沉(erythrocyte sedimentation rate, ESR)]、美国国立卫生研究院卒中量表(national institute of health stroke scale, NIHSS)评分、Barthel指数变化情况。结果:观察组治疗后各项中医证候积分低于对照组,Ashworth量表评级优于对照组,FMA评分高于对照组,差异有统计学意义(P<0.05);观察组治疗后全血高切黏度、全血低切黏度、RBC压积、ESR均低于对照组,差异有统计学意义(P<0.05);观察组治疗后NIHSS评分低于对照组,Barthel指数高于对照组,差异有统计学意义(P<0.05)。结论:化瘀清络脑安汤结合脑栓通胶囊能缓解急性期脑梗死患者肢体痉挛状态,改善血液流变学、运动功能和日常生活能力。
Objective:To observe the influence of Decoction for Removing Stasis and Dredging Meridians and Stabilizing the Mind combined with Capsules for Dredging Cerebral Embolism on limb spasms in patients with acute cerebral infarction.Methods:A prospective analysis study was conducted on 120 patients with acute cerebral infarction admitted to The First Ward of Brain Disease of Jiaozuo Hospital of Traditional Chinese Medicine from January 2019 to December 2020.They were randomly divided into the observation group and the control group,with 60 cases in each group.The control group was treated with Capsules for Dredging Cerebral Embolism,while the observation group was treated with Decoction for Removing Stasis and Dredging Meridians and Stabilizing the Mind combined with Capsules for Dredging Cerebral Embolism.The changes of TCM syndrome score,Ashworth scale score,Fugl-Meyer assessment(FMA)score,hemorheology indexes[including whole blood high shear viscosity,whole blood low shear viscosity,red blood cell(RBC)hematocrit,erythrocyte sedimentation rate(ESR)],the National Institute of Health Stroke Scale(NIHSS)score and Barthel index were observed.Results:After treatment,the scores of various TCM syndromes in the observation group were lower than those in the control group,and the Ashworth scale score was better than that of the control group.The FMA score was higher than that of the control group,and all the differences were statistically significant(P<0.05).After treatment,the whole blood high shear viscosity,whole blood low shear viscosity,RBC hematocrit,and ESR in the observation group were lower than those in the control group,and all the differences were statistically significant(P<0.05);The NIHSS score of the observation group was lower than that of the control group,while the Barthel index was higher than that of the control group,and all the differences were statistically significant(P<0.05).Conclusion:Decoction for Removing Stasis and Dredging Meridians and Stabilizing the Mind combined with Capsules for Dredging Cerebral Embolism can alleviate limb spasms in patients with acute cerebral infarction,improve hemorheology,motor function and ability of daily living.
作者
王明明
张盼盼
WANG Ming-ming;ZHANG Pan-pan(Jiaozuo Hospital of Traditional Chinese Medicine,Jiaozuo,Henan,China,454000)
出处
《河南中医》
2023年第4期576-580,共5页
Henan Traditional Chinese Medicine
基金
河南省中医药科学研究专项课题(2017ZY3014)。
关键词
脑梗死
急性期
肢体痉挛
脑栓通胶囊
化瘀清络脑安汤
cerebral infarction
acute phase
limb spasms
Capsules for Dredging Cerebral Embolism
Decoction for Removing Stasis and Dredging Meridians and Stabilizing the Mind
