摘要
目的观察脉冲电压、电极与消融部位距离对脉冲场消融效果及消融部位温度的影响。方法根据肺静脉直径和电学参数构建三维肺静脉前庭和肺静脉联合模型,以脉冲场消融导管的形状、尺寸和参数构建消融导管模型;评价不同脉冲电压(1000、1200、1500 V)的消融效果,以及电极与消融部位距离(0、0.5、1.5、2.5 mm)对电导率、消融效果及消融区域温度的影响。结果电极贴壁时,以1000、1200及1500 V脉冲消融300μs后,6个消融电极周围均形成有效消融区域并构成连续消融带,且随电压增加有效消融区域增大。电极距离肺静脉前庭2.5 mm时,分别以1000、1200及1500 V脉冲消融300μs,1000 V有效消融范围仅存于电极附近,1200 V有效消融范围较1000 V增加,但未形成连续消融带;1500 V消融范围最大且形成连续消融带。以1000 V脉冲消融300μs,电极与消融部位距离越大,则电导率变化越小。以1000 V、300μs脉冲消融,电极贴壁时有效消融范围大,可形成连续消融带;距离0.5 mm时消融带范围小且不连续;距离>0.5 mm时不能形成连续消融带。以1500 V脉冲消融时,电极附近消融区域温度升高,最高升温10[K];电极与消融部位距离越大,升温幅度越小。结论降低脉冲电压、增大电极与消融部位之间距离均可削弱消融效果、影响消融区域温度。
Objective To observe the impact of pulse voltage and distance between electrode and ablation site on the effect of pulse field ablation and temperature of ablation site.Methods Three-dimensional combined model of pulmonary vein vestibule and pulmonary vein was constructed referring to the pulmonary vein diameter and electrical parameters.The ablation catheter model was constructed according to the shape,size and parameters of the ablation catheter in the real pulse field.The ablation effects were simulated under different pulse voltages(1000,1200,1500 V)and different electrode and ablation site distances(0,0.5,1.5,2.5 mm).The impact of the distance between the electrode and the ablation site on the temperature of the ablation site was observed.Results When the electrode was attached to the wall,after 300μs ablated with 1000,1200 and 1500 V pulses,effective ablation areas were formed around 6 ablation electrodes,forming a complete continuous ablation band,and the effective areas increased with the increase of voltage.When the electrode was 2.5 mm away from the vestibule of the pulmonary vein,after 300μs ablation with 1000,1200,1500 V pulses,the effective ablation range of 1000 V was only near the electrode,of 1200 V was larger than that of 1000 V,but no continuous ablation band formed.The ablation range of 1500 V was the largest,and a complete continuous ablation band was formed.When the ablation electrode was pulsed with 1000 V for 300μs,the farther the electrode from the ablation site,the smaller the conductivity change.Under the ablation of 1000 V pulse voltage for 300μs,when the electrode was completely attached to the wall,the ablation band was wide,and a continuous ablation band formed;when the distance was 0.5 mm,the ablation band formed,but the range was small and discontinuous;when the distance was>0.5 mm,no continuous ablation band formed.For 1500 V pulse ablation,the temperature of the ablation area near the electrode increased,with a maximum temperature rise of 10[K],and the farther the electrode from the ablation site,the smaller the temperature rise.Conclusion Decreased pulse voltage or increased distance between electrode and ablation site might bring weaken ablation effect and affect the temperature of ablation area.
作者
韩赫
贾峰林
王玉杰
薛志孝
HAN He;JIA Fenglin;WANG Yujie;XUE Zhixiao(School of Biomedical Engineering and Technology,Tianjin Medical University,Tianjin 300041,China;Tianjin Intelligent Health Medical Co.,Ltd,Tianjin 300041,China)
出处
《中国介入影像与治疗学》
北大核心
2023年第4期228-232,共5页
Chinese Journal of Interventional Imaging and Therapy
基金
天津市科学技术局科技计划项目(19ZXYXSY00050)。
关键词
心房颤动
脉冲场消融
仿真研究
atrial fibrillation
pulse filed ablation
simulation study
