摘要
大量的研究结果表明骨是一种内分泌器官,其分泌的骨钙素(OC),尤其是未羧化骨钙素(ucOC)可以改善葡萄糖稳态和能量平衡。此外,ucOC对血管系统具有保护作用。有临床研究显示,循环ucOC水平降低与动脉粥样硬化性疾病之间存在关系。本文对OC(主要是ucOC)在葡萄糖代谢和心血管疾病中的作用进行综述。
Numerous studies have suggested that bone is an endocrine organ,and its secretion of osteocalcin(OC),especially uncarboxylated osteocalcin(ucOC),can improve glucose homeostasis and energy balance.In addition,ucOC possesses protective effect on vascular system.Some clinical studies have shown that there is a relationship between the decrease of circulating ucOC level and atherosclerotic diseases.The present article reviews the role of OC(mainly ucOC)in glucose metabolism and cardiovascular diseases.
作者
高胜南
乔虹
GAO Sheng-nan;QIAO Hong(Department of Endocrinology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150081,China)
出处
《心血管康复医学杂志》
CAS
2023年第2期167-169,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
心血管疾病
骨钙素
糖尿病
Cardiovascular diseases
Osteocalcin
Diabetes mellitus
