摘要
溃疡性结肠炎(UC)是发生在结直肠的慢性炎症性疾病,其具体发病机制不明,是世界范围的难治性疾病之一。现代医学认为,UC发病与家族遗传、生活习惯、炎症免疫因素、肠道微生物环境及肠道黏膜屏障等因素有关,主要治疗措施有药物控制炎症、促进黏膜愈合和手术。中医药认为,其病机以脾胃虚弱为本,采取中药内服、针灸、灌肠等多种治疗手段。近年来,中医、西医及中西医结合治疗UC在临床上疗效斐然,能够明显减轻肠道炎症,缓解症状。应进一步探索治疗机制,有效结合中西医治疗措施,完善UC的分期分阶段治疗。
Ulcerative colitis(UC)is a chronic inflammatory disease occurring in the colorectal,and its specific pathogenesis is unknown.UC is one of the intractable diseases worldwide.Modern medicine believes that the pathogenesis of UC is related to family inheritance,living habits,inflammatory immune factors,intestinal microbial environment and intestinal mucosal barrier,etc.The main treatments of UC include medication to control inflammation,promote mucosal healing and surgery.Traditional Chinese medicine believes that its pathogenesis is based on the weakness of the spleen and stomach,and various treatments such as orad administration of traditional Chinese medicine,acupuncture and moxibustion,and enemas are adopted.In recent years,traditional Chinese medicine,Western medicine and the combination of both in the treatment of UC has a remarkable clinical effect,which can significantly reduce intestinal inflammation and relieve symptoms.It is necessary to further explore the treatment mechanism,effectively combine traditional Chinese and Western medicine treatment measures,and improve the phased treatment of UC.
作者
邱小京
郭修田
QIU Xiaojing;GUO Xiutian(Anorectal Department,Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200071,China)
出处
《上海中医药大学学报》
CAS
2023年第2期68-75,共8页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(81873308)。
关键词
溃疡性结肠炎
发病机制
治疗手段
中西医结合
ulcerative colitis
pathogenesis
treatment method
combination of Chinese and western medicine
