摘要
目的探讨分化型甲状腺癌术后、^(131)I治疗前^(99m)TcO_(4)^(-)甲状腺显像评估残甲的临床应用价值。方法选取我科收治的56例分化型甲状腺癌患者,测定甲状腺蛋白(Tg)、甲状腺球蛋白抗体(TgAb)、促甲状腺激素(TSH),行^(99m)TcO_(4)^(-)甲状腺显像、^(131)I显像。分析^(99m)TcO_(4)^(-)甲状腺显像灵敏度、特异度、准确度、阳性预测值、阴性预测值、残甲灶检出率,残甲摄鍀计数与Tg/TSH相关性。结果^(99m)TcO_(4)^(-)甲状腺显像灵敏度86.79%,特异度66.67%,准确度85.71%,阳性预测值97.87%,阴性预测值22.22%,残甲灶检出率69.23%。残甲摄鍀计数与Tg/TSH显著相关(r=0.617,P<0.01)。结论分化型甲状腺癌术后、^(131)I治疗前^(99m)TcO_(4)^(-)甲状腺显像评估残甲临床应用价值较高,具有较高的灵敏度和阳性预测价值以及令人满意的残甲灶检出率。残甲摄鍀计数与Tg/TSH两者显著相关。
Objective To explore the value of ^(99m)TcO_(4)^(-)thyroid scan in detecting remnant thyroid tissue in thyroide ctomized differentiated thyroid cancer.Methods 56 patients with differentiated thyroid cancer admitted to our department were selected.Tg,TgAb and TSH were determined,and ^(99m)TcO_(4)^(-)thyroid scan and ^(131)I scan were performed.The sensitivity,specificity,accuracy,positive predictive value,negative predictive value and detection rate of remnant thyroid tissue,as well as the correlationbetween technetium residue count and Tg/TSH of ^(99m)TcO_(4)^(-)thyroid scan were analyzed.Results The sensitivity,specificity,accuracy,positive predictive value,negative predictive value and detection rate of remnant thyroid tissue of ^(99m)TcO_(4)^(-)thyroid scan were 86.79%,66.67%,85.71%,97.87%,22.22%and 69.23%,respectively.Technetium residue counts were significantly cor related with Tg/TSH.Conclusion ^(99m)TcO_(4)^(-)thyroid scan after differentiated thyroid cancer surgery and before ^(131)I treatment is ofhigh clinical application value in the evaluation of remnant thyroid tissue,with high sensitivity,positive prediction value and sat isfactory detection rate.There is a significant correlation between technetium count and Tg/TSH.
作者
郑贵文
夏志明
姚树展
ZHENG Guiwen;XIA Zhiming;YAO Shuzhan(Department of Nuclear Medicine,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China)
出处
《医学影像学杂志》
2023年第4期559-562,共4页
Journal of Medical Imaging
基金
山东省自然科学基金博士基金及山东省优秀中青年科学家科研奖励基金项目(编号:BS2014YY044)。
